| 1 | Mon Nov 7 | vs TBD | W89-62 | 1-0 | 1.000 | - | | Chiles Center · Portland, OR |
| 2 | Wed Nov 9 | vs FAMU | W91-54 | 2-0 | 1.000 | - | | Chiles Center · Portland, OR |
| 3 | Fri Nov 11 | vs Portland St | W98-91 | 3-0 | 1.000 | - | | Chiles Center · Portland, OR |
| 4 | Mon Nov 14 | at Kent State | L65-77 | 3-1 | .750 | - | | M.A.C. Center · Kent, OH |
| 5 | Thu Nov 17 | at Air Force | W64-51 | 4-1 | .800 | - | | Clune Arena · Colorado Springs, CO |
| 6 | Sat Nov 19 | vs Seattle U | L68-80 | 4-2 | .667 | - | | Chiles Center · Portland, OR |
| 7 | Thu Nov 24 | vs UNC | L81-89 | 4-3 | .571 | - | ESPN | Chiles Center · Portland, OR |
| 8 | Fri Nov 25 | at Villanova | W83-71 | 5-3 | .625 | - | ESPN2 | Finneran Pavilion · Villanova, PA |
| 9 | Sun Nov 27 | at Michigan St | L77-78 | 5-4 | .556 | - | ESPN | Breslin Center · East Lansing, MI |
| 10 | Wed Nov 30 | vsTBD | W100-79 | 6-4 | .600 | - | | Chiles Center · Portland, OR |
| 11 | Sat Dec 3 | vs North Dakota | W90-69 | 7-4 | .636 | - | | Chiles Center · Portland, OR |
| 12 | Mon Dec 5 | vs N Dakota St | L62-67 | 7-5 | .583 | - | | Chiles Center · Portland, OR |
| 13 | Sat Dec 10 | vs New Orleans | W100-61 | 8-5 | .615 | - | | Chiles Center · Portland, OR |
| 14 | Sat Dec 17 | at Oregon | L56-78 | 8-6 | .571 | - | PACN | Matthew Knight Arena · Eugene, OR |
| 15 | Thu Dec 22 | at UC Riverside | L65-76 | 8-7 | .533 | - | | SRC Arena · Riverside, CA |
| 16 | Thu Dec 29 | vs LMU | L72-92 | 8-8 | .500 | - | | Chiles Center · Portland, OR |
| 17 | Sat Dec 31 | at BYU | L58-71 | 8-9 | .471 | - | | Marriott Center · Provo, UT |
| 18 | Sat Jan 7 | at Saint Mary's | L43-85 | 8-10 | .444 | - | | University Credit Union Pavilion · Moraga, CA |
| 19 | Thu Jan 12 | vs San Francisco | W92-87 | 9-10 | .474 | - | ESPNU | Chiles Center · Portland, OR |
| 20 | Sat Jan 14 | at #8Gonzaga | L75-115 | 9-11 | .450 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 21 | Thu Jan 19 | vs San Diego | W88-83 | 10-11 | .476 | - | | Chiles Center · Portland, OR |
| 22 | Sat Jan 21 | vs Pepperdine | W91-76 | 11-11 | .500 | - | | Chiles Center · Portland, OR |
| 23 | Thu Jan 26 | atLMU | L60-79 | 11-12 | .478 | - | | Gersten Pavilion · Los Angeles, CA |
| 24 | Sat Jan 28 | vs#14Gonzaga | L67-82 | 11-13 | .458 | - | | Chiles Center · Portland, OR |
| 25 | Thu Feb 2 | atSan Diego | W80-61 | 12-13 | .480 | - | | Jenny Craig Pavilion · San Diego, CA |
| 26 | Sat Feb 4 | atPepperdine | L93-94 (2OT) | 12-14 | .462 | - | | Firestone Fieldhouse · Malibu, CA |
| 27 | Thu Feb 9 | vs Pacific | W81-73 | 13-14 | .481 | - | | Chiles Center · Portland, OR |
| 28 | Sat Feb 11 | vs#15Saint Mary's | L64-81 | 13-15 | .464 | - | CBS | Chiles Center · Portland, OR |
| 29 | Sat Feb 18 | vs Santa Clara | L84-103 | 13-16 | .448 | - | | Chiles Center · Portland, OR |
| 30 | Thu Feb 23 | atSan Francisco | L89-92 | 13-17 | .433 | - | CBS | War Memorial at the Sobrato Center · San Francisco, CA |
| 31 | Sat Feb 25 | atPacific | L77-81 | 13-18 | .419 | - | | Alex G. Spanos Center · Stockton, CA |
| 32 | Thu Mar 2 | vsSan Diego | W92-74 | 14-18 | .438 | - | | Chiles Center · Portland, OR |
| 33 | Fri Mar 3 | atBYU | L71-82 | 14-19 | .424 | - | | Marriott Center · Provo, UT |
