| 1 | Mon Nov 3 | vs TBD | 7:00 PM | 0-0 | .000 | - | | Ted Grant Court · Syracuse, NY |
| 2 | Thu Nov 6 | atXavier | TBD | 22-12 | .647 | - | | Cintas Center · Cincinnati, OH |
| 3 | Sun Nov 9 | atBowling Green | 2:00 PM | 14-18 | .438 | - | ESPN+ | Stroh Center · Bowling Green, OH |
| 4 | Thu Nov 13 | atUMass | 7:00 PM | 12-20 | .375 | - | ESPN+ | William D. Mullins Memorial Center · Amherst, MA |
| 5 | Mon Nov 17 | vsNiagara | 7:00 PM | 11-20 | .355 | - | | Ted Grant Court · Syracuse, NY |
| 6 | Sat Nov 22 | vsFairfield | 1:00 PM | 12-20 | .375 | - | | Ted Grant Court · Syracuse, NY |
| 7 | Fri Nov 28 | atLafayette | 4:30 PM | 13-20 | .394 | - | ESPN+ | Kirby Sports Center · Easton, PA |
| 8 | Sat Nov 29 | vsMonmouth | 2:00 PM | 13-20 | .394 | - | ESPN+ | Ted Grant Court · Syracuse, NY |
| 9 | Sun Nov 30 | atBall State | 12:00 PM | 14-17 | .452 | - | ESPN+ | Worthen Arena · Muncie, IN |
| 10 | Sat Dec 6 | atBinghamton | 4:00 PM | 15-17 | .469 | - | | Events Center (Binghamton) · Binghamton, NY |
| 11 | Tue Dec 16 | atTexas | TBD | 19-16 | .543 | - | | Moody Center · Austin, TX |
| 12 | Sat Dec 20 | atSt Bonaventure | 2:00 PM | 22-12 | .647 | - | | Reilly Center · Saint Bonaventure, NY |
| 13 | Sun Dec 28 | atBoston College | TBD | 12-19 | .387 | - | | Silvio O. Conte Forum · Chestnut Hill, MA |
| 14 | Fri Jan 2 | atSt Francis PA | TBD | 16-18 | .471 | - | | DeGol Arena · Loretto, PA |
| 15 | Sun Jan 4 | atMercyhurst | TBD | 15-16 | .484 | - | | Mercyhurst Athletic Center · Erie, PA |
| 16 | Thu Jan 8 | vsNew Haven | 7:00 PM | 0-0 | .000 | - | | Ted Grant Court · Syracuse, NY |
| 17 | Sat Jan 10 | vsC Connecticut | 1:00 PM | 25-7 | .781 | - | | Ted Grant Court · Syracuse, NY |
| 18 | Sat Jan 17 | atChicago St | TBD | 4-28 | .125 | - | | Jones Convocation Center · Chicago, IL |
| 19 | Mon Jan 19 | vsLong Island | TBD | 17-16 | .515 | - | | Ted Grant Court · Syracuse, NY |
| 20 | Fri Jan 23 | vsWagner | 7:00 PM | 14-16 | .467 | - | | Ted Grant Court · Syracuse, NY |
| 21 | Sun Jan 25 | atFairleigh | TBD | 13-20 | .394 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 22 | Thu Jan 29 | atLong Island | TBD | 17-16 | .515 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 23 | Sat Jan 31 | vsStonehill | 1:00 PM | 15-17 | .469 | - | | Ted Grant Court · Syracuse, NY |
| 24 | Thu Feb 5 | atWagner | TBD | 14-16 | .467 | - | | Spiro Sports Center · Staten Island, NY |
| 25 | Sat Feb 7 | vsSt Francis PA | 1:00 PM | 16-18 | .471 | - | | Ted Grant Court · Syracuse, NY |
| 26 | Thu Feb 12 | vsMercyhurst | 7:00 PM | 15-16 | .484 | - | | Ted Grant Court · Syracuse, NY |
| 27 | Sat Feb 14 | vsChicago St | 1:00 PM | 4-28 | .125 | - | | Ted Grant Court · Syracuse, NY |
| 28 | Thu Feb 19 | atC Connecticut | 7:00 PM | 25-7 | .781 | - | | William H. Detrick Gymnasium · New Britain, CT |
| 29 | Sat Feb 21 | atStonehill | TBD | 15-17 | .469 | - | | placeholder · sf, ca |
| 30 | Thu Feb 26 | vsFairleigh | 7:00 PM | 13-20 | .394 | - | | Ted Grant Court · Syracuse, NY |
| 31 | Sat Feb 28 | atNew Haven | 1:00 PM | 0-0 | .000 | - | | Jeffery P. Hazell Athletics Center |
