| 1 | Mon Nov 4 | vs CSU Northridge | W70-56 | 1-0 | 1.000 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 2 | Sat Nov 9 | at Canisius | W87-78 | 2-0 | 1.000 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 3 | Wed Nov 13 | at FGCU | W74-65 | 3-0 | 1.000 | - | ESPN+ | Alico Arena · Fort Myers, FL |
| 4 | Sat Nov 16 | vs Le Moyne | W71-52 | 4-0 | 1.000 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 5 | Wed Nov 20 | vs TBD | W76-54 | 5-0 | 1.000 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 6 | Sun Nov 24 | vs Bryant | W85-70 | 6-0 | 1.000 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 7 | Thu Nov 28 | vs Utah State | L67-72 | 6-1 | .857 | - | ESPN2 | Reilly Center · Saint Bonaventure, NY |
| 8 | Fri Nov 29 | at Northern Iowa | W68-56 | 7-1 | .875 | - | ESPNU | McLeod Center · Cedar Falls, IA |
| 9 | Wed Dec 4 | at Bucknell | W64-47 | 8-1 | .889 | - | ESPN+ | Sojka Pavilion · Lewisburg, PA |
| 10 | Sat Dec 7 | vs Buffalo | W65-55 | 9-1 | .900 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 11 | Sat Dec 14 | at Providence | W74-70 | 10-1 | .909 | - | CBS | Amica Mutual Pavilion · Providence, RI |
| 12 | Tue Dec 17 | at Siena | W65-48 | 11-1 | .917 | - | ESPN+ | MVP Arena · Albany, NY |
| 13 | Sat Dec 21 | vs Niagara | W71-52 | 12-1 | .923 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 14 | Tue Dec 31 | vs VCU | W77-75 | 13-1 | .929 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 15 | Sat Jan 4 | at Fordham | W86-66 | 14-1 | .933 | - | ESPN+ | Rose Hill Gymnasium · Bronx, NY |
| 16 | Wed Jan 8 | at Saint Louis | L68-73 | 14-2 | .875 | - | Peacock | Chaifetz Arena · St. Louis, MO |
| 17 | Sat Jan 11 | vs La Salle | L82-83 (OT) | 14-3 | .824 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 18 | Wed Jan 15 | vs Richmond | W63-49 | 15-3 | .833 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 19 | Sat Jan 18 | at Duquesne | L57-75 | 15-4 | .789 | - | ESPN+ | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 20 | Tue Jan 21 | vs George Mason | L62-75 | 15-5 | .750 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 21 | Fri Jan 24 | atVCU | L61-75 | 15-6 | .714 | - | ESPNU | Stuart C. Siegel Center · Richmond, VA |
| 22 | Tue Jan 28 | vs Dayton | W75-53 | 16-6 | .727 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 23 | Sat Feb 1 | vsFordham | W74-72 | 17-6 | .739 | - | USA Net | Reilly Center · Saint Bonaventure, NY |
| 24 | Tue Feb 4 | at Loyola Chicago | L53-77 | 17-7 | .708 | - | CBS | Joseph J. Gentile Arena · Chicago, IL |
| 25 | Sun Feb 9 | vs G Washington | L52-62 | 17-8 | .680 | - | USA Net | Reilly Center · Saint Bonaventure, NY |
| 26 | Wed Feb 12 | at Rhode Island | L64-68 | 17-9 | .654 | - | ESPN+ | Ryan Center · Kingston, RI |
| 27 | Sat Feb 15 | at UMass | W73-59 | 18-9 | .667 | - | ESPN+ | William D. Mullins Memorial Center · Amherst, MA |
Saint Joseph's
Davidson