| 1 | Mon Nov 3 | vs Bradley | 11:00 AM | 28-9 | .757 | - | | Reilly Center · Saint Bonaventure, NY |
| 2 | Sat Nov 8 | vsCanisius | TBD | 3-28 | .097 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 3 | Wed Nov 12 | vsSiena | TBD | 14-18 | .438 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 4 | Sat Nov 15 | vsYoungstown St | TBD | 21-13 | .618 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 5 | Thu Nov 20 | vsRobert Morris | TBD | 26-9 | .743 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 6 | Tue Nov 25 | at#25UNC | 6:00 PM | 23-14 | .622 | - | FS1 | Dean E. Smith Center · Chapel Hill, NC |
| 7 | Thu Nov 27 | atE Carolina | 12:00 PM | 19-14 | .576 | - | FS1 | Williams Arena at Minges Coliseum · Greenville, NC |
| 8 | Sun Nov 30 | atFAU | TBD | 18-16 | .529 | - | | FAU Arena · Boca Raton, FL |
| 9 | Wed Dec 3 | vsTBD | TBD | 0-0 | .000 | - | | Reilly Center · Saint Bonaventure, NY |
| 10 | Sat Dec 6 | atBuffalo | 2:00 PM | 9-22 | .290 | - | | Alumni Arena · Buffalo, NY |
| 11 | Wed Dec 10 | vsColgate | 7:00 PM | 14-19 | .424 | - | | Reilly Center · Saint Bonaventure, NY |
| 12 | Sat Dec 13 | atOhio | 4:00 PM | 16-16 | .500 | - | | Convocation Center (OH) · Athens, OH |
| 13 | Sat Dec 20 | vsLe Moyne | 2:00 PM | 9-23 | .281 | - | | Reilly Center · Saint Bonaventure, NY |
| 14 | Wed Dec 31 | atVCU | TBD | 28-7 | .800 | - | | Stuart C. Siegel Center · Richmond, VA |
| 15 | Wed Jan 7 | vsRichmond | TBD | 10-22 | .313 | - | | Reilly Center · Saint Bonaventure, NY |
| 16 | Sat Jan 10 | vsFordham | 12:00 PM | 12-21 | .364 | - | | Reilly Center · Saint Bonaventure, NY |
| 17 | Wed Jan 14 | atSaint Joseph's | 7:00 PM | 22-13 | .629 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 18 | Sat Jan 17 | atLa Salle | 2:30 PM | 14-19 | .424 | - | | Tom Gola Arena · Philadelphia, PA |
| 19 | Tue Jan 20 | vsLoyola Chicago | TBD | 25-12 | .676 | - | | Reilly Center · Saint Bonaventure, NY |
| 20 | Fri Jan 23 | vsSaint Louis | TBD | 19-15 | .559 | - | | Reilly Center · Saint Bonaventure, NY |
| 21 | Wed Jan 28 | atDuquesne | TBD | 13-19 | .406 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 22 | Sat Jan 31 | vsGeorge Mason | 6:30 PM | 27-9 | .750 | - | | Reilly Center · Saint Bonaventure, NY |
| 23 | Tue Feb 3 | atDayton | TBD | 23-11 | .676 | - | | UD Arena · Dayton, OH |
| 24 | Sat Feb 7 | atFordham | 2:00 PM | 12-21 | .364 | - | | Rose Hill Gymnasium · Bronx, NY |
| 25 | Sat Feb 14 | vsDuquesne | TBD | 13-19 | .406 | - | | Reilly Center · Saint Bonaventure, NY |
| 26 | Wed Feb 18 | vsSaint Joseph's | TBD | 22-13 | .629 | - | | Reilly Center · Saint Bonaventure, NY |
| 27 | Sat Feb 21 | atRichmond | TBD | 10-22 | .313 | - | | Robins Center · Richmond, VA |
| 28 | Wed Feb 25 | vsRhode Island | TBD | 18-13 | .581 | - | | Reilly Center · Saint Bonaventure, NY |
| 29 | Sat Feb 28 | atGeorge Mason | 2:00 PM | 27-9 | .750 | - | | EagleBank Arena · Fairfax, VA |
| 30 | Wed Mar 4 | atG Washington | TBD | 21-13 | .618 | - | | Charles E. Smith Center · Washington, D.C. |
| 31 | Sat Mar 7 | vsDavidson | TBD | 17-16 | .515 | - | | Reilly Center · Saint Bonaventure, NY |
