| 1 | Tue Nov 5 | vs TBD | W103-60 | 1-0 | 1.000 | - | | Jones Convocation Center · Chicago, IL |
| 2 | Sat Nov 9 | vsLoyola MD | L85-98 | 1-1 | .500 | - | | Jones Convocation Center · Chicago, IL |
| 3 | Tue Nov 12 | atE Illinois | L34-98 | 1-2 | .333 | - | | Lantz Arena · Charleston, IL |
| 4 | Sat Nov 16 | atPurdue | L49-93 | 1-3 | .250 | - | | Mackey Arena · West Lafayette, IN |
| 5 | Tue Nov 19 | vsTBD | W89-77 | 2-3 | .400 | - | | Jones Convocation Center · Chicago, IL |
| 6 | Wed Nov 20 | vsTBD | W79-66 | 3-3 | .500 | - | | Jones Convocation Center · Chicago, IL |
| 7 | Mon Nov 25 | atFlorida St | L56-113 | 3-4 | .429 | - | | Donald L. Tucker Center · Tallahassee, FL |
| 8 | Fri Nov 29 | vsJ'Ville St | L62-71 | 3-5 | .375 | - | | Jones Convocation Center · Chicago, IL |
| 9 | Sat Nov 30 | atAlabama St | L54-67 | 3-6 | .333 | - | | Dunn-Oliver Acadome · Montgomery, AL |
| 10 | Wed Dec 4 | atSIUE | W89-81 | 4-6 | .400 | - | | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 11 | Fri Dec 6 | atTennessee St | L74-80 | 4-7 | .364 | - | | Gentry Center · Nashville, TN |
| 12 | Tue Dec 17 | vsOral Roberts | L59-97 | 4-8 | .333 | - | | Jones Convocation Center · Chicago, IL |
| 13 | Thu Dec 19 | vsN Illinois | L60-75 | 4-9 | .308 | - | | Jones Convocation Center · Chicago, IL |
| 14 | Sun Dec 22 | atIndiana St | L64-85 | 4-10 | .286 | - | | Hulman Center · Terre Haute, IN |
| 15 | Mon Dec 30 | atMissouri | L33-91 | 4-11 | .267 | - | | Mizzou Arena · Columbia, MO |
| 16 | Thu Jan 2 | vsUtah Valley | L73-94 | 4-12 | .250 | - | | Jones Convocation Center · Chicago, IL |
| 17 | Sat Jan 4 | vsSeattle U | L54-86 | 4-13 | .235 | - | | Jones Convocation Center · Chicago, IL |
| 18 | Thu Jan 9 | atNew Mexico St | L54-93 | 4-14 | .222 | - | | Pan American Center · Las Cruces, NM |
| 19 | Sat Jan 11 | atUT Rio Grande | L63-87 | 4-15 | .211 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 20 | Thu Jan 16 | vsGrand Canyon | L64-78 | 4-16 | .200 | - | | Jones Convocation Center · Chicago, IL |
| 21 | Sun Jan 19 | vsBakersfield | L54-72 | 4-17 | .190 | - | | Jones Convocation Center · Chicago, IL |
| 22 | Wed Jan 22 | atCA Baptist | L53-85 | 4-18 | .182 | - | | CBU Events Center · Riverside, CA |
| 23 | Sat Feb 1 | vsKansas City | L51-69 | 4-19 | .174 | - | | Jones Convocation Center · Chicago, IL |
| 24 | Thu Feb 6 | vsNew Mexico St | L49-71 | 4-20 | .167 | - | | Jones Convocation Center · Chicago, IL |
| 25 | Sat Feb 8 | vsUT Rio Grande | L64-75 | 4-21 | .160 | - | | Jones Convocation Center · Chicago, IL |
| 26 | Thu Feb 13 | atBakersfield | L54-64 | 4-22 | .154 | - | | Icardo Center · Bakersfield, CA |
| 27 | Sat Feb 15 | atGrand Canyon | L47-71 | 4-23 | .148 | - | | GCU Arena · Phoenix, AZ |
| 28 | Sat Feb 22 | vsCA Baptist | L53-95 | 4-24 | .143 | - | | Jones Convocation Center · Chicago, IL |
| 29 | Sat Feb 29 | atKansas City | L58-80 | 4-25 | .138 | - | | Swinney Recreation Center · Kansas City, MO |
