| 1 | Wed Nov 25 | at UMass Lowell | L68-76 | 0-1 | .000 | - | | Costello Athletic Center · Lowell, MA |
| 2 | Thu Nov 26 | vsTowson | W79-68 | 1-1 | .500 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 3 | Fri Nov 27 | vsVirginia | W61-60 | 2-1 | .667 | - | ESPN | War Memorial at the Sobrato Center · San Francisco, CA |
| 4 | Sun Nov 29 | atRhode Island | L71-84 | 2-2 | .500 | - | ESPNU | Ryan Center · Kingston, RI |
| 5 | Wed Dec 2 | atNevada | W85-60 | 3-2 | .600 | - | | Barclays Center · Brooklyn, NY |
| 6 | Fri Dec 4 | atCal Poly | W88-60 | 4-2 | .667 | - | | Robert A. Mott Athletics Center · San Luis Obispo, CA |
| 8 | Thu Dec 10 | vsLong Beach St | W107-62 | 5-2 | .714 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 9 | Sun Dec 13 | atCalifornia | L70-72 | 5-3 | .625 | - | PACN | Haas Pavilion · Berkeley, CA |
| 11 | Thu Dec 17 | atOregon | L64-74 | 5-4 | .556 | - | PACN | Matthew Knight Arena · Eugene, OR |
| 12 | Sun Dec 20 | vsGrand Canyon | W68-65 | 6-4 | .600 | - | | T-Mobile Arena · Las Vegas, NV |
| 13 | Thu Dec 31 | vsSan Diego | W70-62 | 7-4 | .636 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 14 | Sat Jan 2 | at1Gonzaga | L62-85 | 7-5 | .583 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 15 | Thu Jan 7 | vsPortland | W88-64 | 8-5 | .615 | - | ESPNU | War Memorial at the Sobrato Center · San Francisco, CA |
| 16 | Sat Jan 9 | atLMU | PPD | 11-14 | .440 | - | | Gersten Pavilion · Los Angeles, CA |
| 17 | Sun Jan 10 | atLMU | L60-68 | 8-6 | .571 | - | | Gersten Pavilion · Los Angeles, CA |
| 18 | Thu Jan 14 | atPortland | W79-63 | 9-6 | .600 | - | | Chiles Center · Portland, OR |
| 19 | Sat Jan 16 | vsBYU | L63-72 | 9-7 | .563 | - | ESPN | War Memorial at the Sobrato Center · San Francisco, CA |
| 20 | Thu Jan 21 | atSanta Clara | W73-50 | 10-7 | .588 | - | | Leavey Center · Santa Clara, CA |
| 21 | Sat Jan 23 | vsSaint Mary's | L63-67 | 10-8 | .556 | - | CBSSN | War Memorial at the Sobrato Center · San Francisco, CA |
| 22 | Wed Feb 10 | vsPepperdine | L68-76 | 10-9 | .526 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 23 | Sat Feb 13 | vs1Gonzaga | L61-100 | 10-10 | .500 | - | ESPN2 | War Memorial at the Sobrato Center · San Francisco, CA |
| 24 | Thu Feb 18 | vsLMU | L63-68 | 10-11 | .476 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 25 | Thu Feb 25 | atBYU | L73-79 | 10-12 | .455 | - | CBSSN | Marriott Center · Provo, UT |
| 26 | Sat Feb 27 | atPacific | L69-76 | 10-13 | .435 | - | | Alex G. Spanos Center · Stockton, CA |
| 27 | Thu Mar 4 | vsSan Diego | W67-51 | 11-13 | .458 | - | | Orleans Arena · Las Vegas, NV |
| 28 | Fri Mar 5 | atLMU | L66-70 | 11-14 | .440 | - | | Orleans Arena · Las Vegas, NV |
