| 1 | Tue Nov 5 | vs TBD | W101-50 | 1-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 2 | Sat Nov 9 | vsPrinceton | W82-72 | 2-0 | 1.000 | - | | Chase Center · San Francisco, CA |
| 3 | Mon Nov 11 | vsYale | W84-79 (OT) | 3-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 4 | Sat Nov 16 | atS Illinois | W76-60 | 4-0 | 1.000 | - | | Banterra Center · Carbondale, IL |
| 5 | Tue Nov 19 | vsBakersfield | W100-70 | 5-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 6 | Sat Nov 23 | vsSam Houston | W90-81 | 6-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 7 | Tue Nov 26 | vsHampton | W89-73 | 7-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 8 | Fri Nov 29 | atHawai'i | L75-85 | 7-1 | .875 | - | | Stan Sheriff Center · Honolulu, HI |
| 9 | Tue Dec 3 | vsArizona St | L67-71 | 7-2 | .778 | - | CBSSN | War Memorial at the Sobrato Center · San Francisco, CA |
| 10 | Wed Dec 4 | vsCalifornia | W76-64 | 8-2 | .800 | - | CBSSN | War Memorial at the Sobrato Center · San Francisco, CA |
| 11 | Sat Dec 14 | atFullerton | W91-69 | 9-2 | .818 | - | | Titan Gym · Fullerton, CA |
| 12 | Tue Dec 17 | atStanford | L56-64 | 9-3 | .750 | - | PACN | Maples Pavilion · Stanford, CA |
| 13 | Sat Dec 21 | vsUC Davis | W93-84 | 10-3 | .769 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 14 | Mon Dec 23 | atFresno St | W71-69 | 11-3 | .786 | - | | Save Mart Center · Fresno, CA |
| 15 | Mon Dec 30 | vsHarvard | L81-84 (OT) | 11-4 | .733 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 16 | Thu Jan 2 | vsSaint Mary's | L58-69 | 11-5 | .688 | - | ESPNU | War Memorial at the Sobrato Center · San Francisco, CA |
| 17 | Sat Jan 4 | atPortland | L65-76 | 11-6 | .647 | - | | Chiles Center · Portland, OR |
| 18 | Thu Jan 9 | vsSanta Clara | W80-61 | 12-6 | .667 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 19 | Sat Jan 11 | atPacific | W79-75 | 13-6 | .684 | - | | Alex G. Spanos Center · Stockton, CA |
| 20 | Sat Jan 18 | vsLMU | W61-53 | 14-6 | .700 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 21 | Thu Jan 23 | atSaint Mary's | L48-58 | 14-7 | .667 | - | CBSSN | University Credit Union Pavilion · Moraga, CA |
| 22 | Sat Jan 25 | vsBYU | W83-82 | 15-7 | .682 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 23 | Thu Jan 30 | atSan Diego | W69-44 | 16-7 | .696 | - | | Jenny Craig Pavilion · San Diego, CA |
| 24 | Sat Feb 1 | vs2Gonzaga | L79-83 | 16-8 | .667 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 25 | Thu Feb 6 | vsPacific | L48-60 | 16-9 | .640 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 26 | Sat Feb 8 | atBYU | L76-90 | 16-10 | .615 | - | | Marriott Center · Provo, UT |
| 27 | Thu Feb 13 | atSanta Clara | W70-61 | 17-10 | .630 | - | | Leavey Center · Santa Clara, CA |
| 28 | Thu Feb 20 | at2Gonzaga | L54-71 | 17-11 | .607 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 29 | Sat Feb 22 | vsPepperdine | W63-61 (OT) | 18-11 | .621 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 30 | Thu Feb 27 | vsPortland | W81-65 | 19-11 | .633 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 31 | Sat Feb 29 | atLMU | W69-67 | 20-11 | .645 | - | | Gersten Pavilion · Los Angeles, CA |
| 32 | Fri Mar 6 | vsLMU | W82-53 | 21-11 | .656 | - | | Orleans Arena · Las Vegas, NV |
| 33 | Sat Mar 7 | atPacific | W72-54 | 22-11 | .667 | - | ESPN2 | Orleans Arena · Las Vegas, NV |
| 34 | Mon Mar 9 | atGonzaga | L77-81 | 22-12 | .647 | - | ESPN | Orleans Arena · Las Vegas, NV |
