| 1 | Mon Nov 7 | vs Texas So | W90-77 | 1-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 2 | Thu Nov 10 | vsCal Poly | W60-48 | 2-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 3 | Sun Nov 13 | vsTBD | W88-71 | 3-0 | 1.000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 4 | Wed Nov 16 | atFresno St | W67-60 | 4-0 | 1.000 | - | | Save Mart Center · Fresno, CA |
| 5 | Mon Nov 21 | vsNorthern Iowa | W75-69 | 5-0 | 1.000 | - | CBSSN | T-Mobile Center · Kansas City, MOS |
| 6 | Tue Nov 22 | atWichita St | W67-63 | 6-0 | 1.000 | - | CBSSN | T-Mobile Center · Kansas City, MOS |
| 7 | Fri Nov 25 | atDavidson | L80-89 | 6-1 | .857 | - | | John M. Belk Arena · Davidson, NC |
| 8 | Wed Nov 30 | vsLittle Rock | W90-68 | 7-1 | .875 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 9 | Sun Dec 4 | vsUtah State | L64-82 | 7-2 | .778 | - | | Chase Center · San Francisco, CA |
| 10 | Wed Dec 7 | vsMerrimack | W69-51 | 8-2 | .800 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 11 | Mon Dec 12 | atNew Mexico | L64-67 | 8-3 | .727 | - | | The Pit · Albuquerque, NM |
| 12 | Sat Dec 17 | atUNLV | W75-73 | 9-3 | .750 | - | | Thomas & Mack Center · Las Vegas, NV |
| 13 | Mon Dec 19 | vsUT Arlington | L63-68 | 9-4 | .692 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 14 | Wed Dec 21 | vs25Arizona St | W97-60 | 10-4 | .714 | - | CBSSN | War Memorial at the Sobrato Center · San Francisco, CA |
| 15 | Thu Dec 22 | vsTBD | W85-53 | 11-4 | .733 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 16 | Thu Dec 29 | atSanta Clara | L67-79 | 11-5 | .688 | - | | Leavey Center · Santa Clara, CA |
| 17 | Sat Dec 31 | vsSan Diego | L68-80 | 11-6 | .647 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 18 | Thu Jan 5 | vs9Gonzaga | L75-77 | 11-7 | .611 | - | ESPN2 | War Memorial at the Sobrato Center · San Francisco, CA |
| 19 | Sat Jan 7 | atLMU | W72-70 | 12-7 | .632 | - | | Gersten Pavilion · Los Angeles, CA |
| 20 | Thu Jan 12 | atPortland | L87-92 | 12-8 | .600 | - | ESPNU | Chiles Center · Portland, OR |
| 21 | Sat Jan 14 | vsSaint Mary's | L61-78 | 12-9 | .571 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 22 | Thu Jan 19 | vsPacific | W78-57 | 13-9 | .591 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 23 | Sat Jan 21 | vsBYU | W82-74 | 14-9 | .609 | - | CBSSN | War Memorial at the Sobrato Center · San Francisco, CA |
| 24 | Sat Jan 28 | atSan Diego | W94-81 | 15-9 | .625 | - | | Jenny Craig Pavilion · San Diego, CA |
| 25 | Thu Feb 2 | at18Saint Mary's | L59-68 | 15-10 | .600 | - | ESPNU | University Credit Union Pavilion · Moraga, CA |
| 26 | Sat Feb 4 | vsSanta Clara | L70-84 | 15-11 | .577 | - | ESPNU | War Memorial at the Sobrato Center · San Francisco, CA |
| 27 | Thu Feb 9 | at16Gonzaga | L81-99 | 15-12 | .556 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 28 | Sat Feb 11 | vsPepperdine | W88-80 | 16-12 | .571 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 29 | Thu Feb 16 | atPacific | W76-68 | 17-12 | .586 | - | | Alex G. Spanos Center · Stockton, CA |
| 30 | Thu Feb 23 | vsPortland | W92-89 | 18-12 | .600 | - | CBSSN | War Memorial at the Sobrato Center · San Francisco, CA |
| 31 | Sat Feb 25 | atBYU | L61-87 | 18-13 | .581 | - | ESPNU | Marriott Center · Provo, UT |
| 32 | Fri Mar 3 | vsPacific | W80-63 | 19-13 | .594 | - | | Orleans Arena · Las Vegas, NV |
| 33 | Sun Mar 5 | atSanta Clara | W93-87 (2OT) | 20-13 | .606 | - | ESPN2 | Orleans Arena · Las Vegas, NV |
| 34 | Mon Mar 6 | atGonzaga | L73-84 | 20-14 | .588 | - | ESPN2 | Orleans Arena · Las Vegas, NV |
