| 1 | Mon Nov 7 | vs Nicholls | W117-75 | 1-0 | 1.000 | #17 | PACN | McKale Center · Tucson, AZ |
| 2 | Fri Nov 11 | vs Southern | W95-78 | 2-0 | 1.000 | - | PACN | McKale Center · Tucson, AZ |
| 3 | Thu Nov 17 | vs Utah Tech | W104-77 | 3-0 | 1.000 | #14 | PACN | McKale Center · Tucson, AZ |
| 4 | Mon Nov 21 | vs Cincinnati | W101-93 | 4-0 | 1.000 | - | ESPN2 | McKale Center · Tucson, AZ |
| 5 | Tue Nov 22 | vs SDSU | W87-70 | 5-0 | 1.000 | - | ESPN | McKale Center · Tucson, AZ |
| 6 | Wed Nov 23 | vs Creighton | W81-79 | 6-0 | 1.000 | - | ESPN | McKale Center · Tucson, AZ |
| 7 | Thu Dec 1 | at Utah | L66-81 | 6-1 | .857 | #4 | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 8 | Sun Dec 4 | vs California | W81-68 | 7-1 | .875 | #4 | PACN | McKale Center · Tucson, AZ |
| 9 | Sat Dec 10 | vs Indiana | W89-75 | 8-1 | .889 | - | FOX | McKale Center · Tucson, AZ |
| 10 | Tue Dec 13 | vs Texas A&M-CC | W99-61 | 9-1 | .900 | #9 | | McKale Center · Tucson, AZ |
| 11 | Sat Dec 17 | vs #6Tennessee | W75-70 | 10-1 | .909 | #9 | ESPN2 | McKale Center · Tucson, AZ |
| 12 | Tue Dec 20 | vs Montana St | W85-64 | 11-1 | .917 | #5 | PACN | McKale Center · Tucson, AZ |
| 13 | Thu Dec 22 | vs Morgan St | W93-68 | 12-1 | .923 | #5 | PACN | McKale Center · Tucson, AZ |
| 14 | Sat Dec 31 | at Arizona St | W69-60 | 13-1 | .929 | #5 | FOX | Desert Financial Arena · Tempe, AZ |
| 15 | Thu Jan 5 | vs Washington | W70-67 | 14-1 | .933 | #5 | FS1 | McKale Center · Tucson, AZ |
| 16 | Sat Jan 7 | vs Washington St | L61-74 | 14-2 | .875 | #5 | PACN | McKale Center · Tucson, AZ |
| 17 | Thu Jan 12 | at Oregon St | W86-74 | 15-2 | .882 | #9 | ESPN2 | Gill Coliseum · Corvallis, OR |
| 18 | Sat Jan 14 | at Oregon | L68-87 | 15-3 | .833 | #9 | ESPN | Matthew Knight Arena · Eugene, OR |
| 19 | Thu Jan 19 | vs USC | W81-66 | 16-3 | .842 | #11 | PACN | McKale Center · Tucson, AZ |
| 20 | Sat Jan 21 | vs #5UCLA | W58-52 | 17-3 | .850 | #11 | ABC | McKale Center · Tucson, AZ |
| 21 | Thu Jan 26 | atWashington St | W63-58 | 18-3 | .857 | #6 | FS1 | Friel Court at Beasley Coliseum · Pullman, WA |
| 22 | Sat Jan 28 | atWashington | W95-72 | 19-3 | .864 | #6 | FOX | Alaska Airlines Arena · Seattle, WA |
| 23 | Thu Feb 2 | vsOregon | W91-76 | 20-3 | .870 | #5 | ESPN | McKale Center · Tucson, AZ |
| 24 | Sat Feb 4 | vsOregon St | W84-52 | 21-3 | .875 | #5 | PACN | McKale Center · Tucson, AZ |
| 25 | Thu Feb 9 | atCalifornia | W85-62 | 22-3 | .880 | #4 | PACN | Haas Pavilion · Berkeley, CA |
| 26 | Sat Feb 11 | at Stanford | L79-88 | 22-4 | .846 | #4 | ESPN2 | Maples Pavilion · Stanford, CA |
| 27 | Thu Feb 16 | vsUtah | W88-62 | 23-4 | .852 | #8 | PACN | McKale Center · Tucson, AZ |
| 28 | Sat Feb 18 | vs Colorado | W78-68 | 24-4 | .857 | #8 | ESPN2 | McKale Center · Tucson, AZ |
| 29 | Sat Feb 25 | vsArizona St | L88-89 | 24-5 | .828 | #7 | CBS | McKale Center · Tucson, AZ |
| 30 | Thu Mar 2 | atUSC | W87-81 | 25-5 | .833 | #8 | ESPN | Galen Center · Los Angeles, CA |
| 31 | Sat Mar 4 | at#4UCLA | L73-82 | 25-6 | .806 | #8 | ESPN | Pauley Pavilion · Los Angeles, CA |
| 32 | Thu Mar 9 | vsStanford | W95-84 | 26-6 | .813 | - | PACN | McKale Center · Tucson, AZ |
| 33 | Fri Mar 10 | vsArizona St | W78-59 | 27-6 | .818 | - | ESPN | McKale Center · Tucson, AZ |
| 34 | Sat Mar 11 | atUCLA | W61-59 | 28-6 | .824 | - | ESPN | Pauley Pavilion · Los Angeles, CA |
| 35 | Thu Mar 16 | vs #15Princeton | L55-59 | 28-7 | .800 | #2 | TNT | McKale Center · Tucson, AZ |
