| 2 | Fri Nov 27 | vs Grambling | W74-55 | 1-0 | 1.000 | - | | McKale Center · Tucson, AZ |
| 4 | Wed Dec 2 | vsColorado | PPD | 17-9 | .654 | - | | McKale Center · Tucson, AZ |
| 5 | Sat Dec 5 | vsE Washington | W70-67 | 2-0 | 1.000 | - | PACN | McKale Center · Tucson, AZ |
| 6 | Mon Dec 7 | vsN Arizona | W96-53 | 3-0 | 1.000 | - | | McKale Center · Tucson, AZ |
| 7 | Wed Dec 9 | vsBakersfield | W85-60 | 4-0 | 1.000 | - | PACN | McKale Center · Tucson, AZ |
| 8 | Sat Dec 12 | vsUTEP | W69-61 | 5-0 | 1.000 | - | PACN | McKale Center · Tucson, AZ |
| 10 | Sat Dec 19 | atStanford | L75-78 | 5-1 | .833 | - | PACN | Maples Pavilion · Stanford, CA |
| 12 | Tue Dec 22 | vsMontana | W70-64 | 6-1 | .857 | - | PACN | McKale Center · Tucson, AZ |
| 13 | Mon Dec 28 | vsColorado | W88-74 | 7-1 | .875 | - | PACN | McKale Center · Tucson, AZ |
| 14 | Thu Dec 31 | atWashington | W80-53 | 8-1 | .889 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 15 | Sat Jan 2 | atWashington St | W86-82 (2OT) | 9-1 | .900 | - | PACN | Friel Court at Beasley Coliseum · Pullman, WA |
| 16 | Thu Jan 7 | vsUSC | L73-87 | 9-2 | .818 | - | ESPN2 | McKale Center · Tucson, AZ |
| 17 | Sat Jan 9 | vsUCLA | L76-81 | 9-3 | .750 | - | ESPN | McKale Center · Tucson, AZ |
| 18 | Thu Jan 14 | atOregon St | W98-64 | 10-3 | .769 | - | | Gill Coliseum · Corvallis, OR |
| 19 | Sat Jan 16 | at#22Oregon | PPD | 17-9 | .654 | - | | Matthew Knight Arena · Eugene, OR |
| 20 | Thu Jan 21 | atArizona St | W84-82 | 11-3 | .786 | - | ESPN | Desert Financial Arena · Tempe, AZ |
| 21 | Mon Jan 25 | vsArizona St | W80-67 | 12-3 | .800 | - | ESPN2 | McKale Center · Tucson, AZ |
| 22 | Thu Jan 28 | vsStanford | L64-73 | 12-4 | .750 | - | ESPN2 | McKale Center · Tucson, AZ |
| 23 | Sat Jan 30 | vsCalifornia | W71-50 | 13-4 | .765 | - | PACN | McKale Center · Tucson, AZ |
| 24 | Thu Feb 4 | atUtah | L58-73 | 13-5 | .722 | - | FS1 | Jon M. Huntsman Center · Salt Lake City, UT |
| 25 | Sat Feb 6 | atColorado | L79-82 | 13-6 | .684 | - | FS1 | CU Events Center · Boulder, CO |
| 26 | Thu Feb 11 | vsOregon St | W70-61 | 14-6 | .700 | - | PACN | McKale Center · Tucson, AZ |
| 27 | Sat Feb 13 | vsOregon | L61-63 | 14-7 | .667 | - | ESPN2 | McKale Center · Tucson, AZ |
| 28 | Thu Feb 18 | atUCLA | L60-74 | 14-8 | .636 | - | ESPN2 | Pauley Pavilion · Los Angeles, CA |
| 29 | Sat Feb 20 | at#17USC | W81-72 | 15-8 | .652 | - | | Galen Center · Los Angeles, CA |
| 30 | Thu Feb 25 | vsWashington St | W69-53 | 16-8 | .667 | - | FS1 | McKale Center · Tucson, AZ |
| 31 | Sat Feb 27 | vsWashington | W75-74 | 17-8 | .680 | - | CBS | McKale Center · Tucson, AZ |
| 32 | Mon Mar 1 | atOregon | L69-80 | 17-9 | .654 | - | ESPN2 | Matthew Knight Arena · Eugene, OR |
