| 1 | Mon Nov 4 | vs TBD | W96-41 | 1-0 | 1.000 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 2 | Wed Nov 6 | vsTBD | W104-60 | 2-0 | 1.000 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 3 | Sat Nov 9 | vs JMU | W83-69 | 3-0 | 1.000 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 4 | Tue Nov 12 | at William & Mary | L73-84 | 3-1 | .750 | - | FloSports | Kaplan Arena · Williamsburg, VA |
| 5 | Sat Nov 16 | at Hampton | W67-58 | 4-1 | .800 | - | | Convocation Center (VA) · Hampton, VA |
| 6 | Wed Nov 20 | at Stanford | L63-70 | 4-2 | .667 | - | ESPN+ | Maples Pavilion · Stanford, CA |
| 7 | Fri Nov 22 | at Grand Canyon | L73-91 | 4-3 | .571 | - | ESPN+ | GCU Arena · Phoenix, AZ |
| 8 | Mon Nov 25 | at UC Davis | W76-55 | 5-3 | .625 | - | ESPN+ | University Credit Union Center · Davis, CA |
| 9 | Sun Dec 1 | at Stony Brook | W77-66 | 6-3 | .667 | - | | Island FCU Arena · Stony Brook, NY |
| 10 | Mon Dec 9 | vs Hofstra | L67-80 | 6-4 | .600 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 11 | Wed Dec 11 | at Baylor | L69-94 | 6-5 | .545 | - | ESPN+ | Ferrell Center · Waco, TX |
| 12 | Sun Dec 15 | at N Kentucky | L62-71 | 6-6 | .500 | - | ESPN+ | Truist Arena · Highland Heights, KY |
| 13 | Thu Dec 19 | vs Alabama St | W71-54 | 7-6 | .538 | - | ESPNU | Joseph G. Echols Hall · Norfolk, VA |
| 14 | Fri Dec 20 | at Grambling | W76-70 | 8-6 | .571 | - | ESPNU | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 15 | Sun Dec 29 | at High Point | W77-74 | 9-6 | .600 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 16 | Tue Dec 31 | at #1Tennessee | L52-67 | 9-7 | .563 | - | ESPN+ | Thompson-Boling Arena · Knoxville, TN |
| 17 | Sat Jan 4 | vs MD-Eastern | W81-59 | 10-7 | .588 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 18 | Mon Jan 6 | at Delaware St | W73-64 | 11-7 | .611 | - | ESPN+ | Memorial Hall (Dover, DE) · Dover, DE |
| 19 | Sat Jan 11 | vs Coppin St | W92-69 | 12-7 | .632 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 20 | Mon Jan 13 | at Morgan St | L74-78 | 12-8 | .600 | - | ESPN+ | Hill Field House · Baltimore, MD |
| 21 | Mon Jan 20 | vsTBD | W105-42 | 13-8 | .619 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 22 | Sat Jan 25 | vs Howard | W92-75 | 14-8 | .636 | - | ESPNU | Joseph G. Echols Hall · Norfolk, VA |
| 23 | Sat Feb 1 | vs SC State | W67-65 (OT) | 15-8 | .652 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 24 | Mon Feb 3 | vs NC Central | W81-78 | 16-8 | .667 | - | ESPNU | Joseph G. Echols Hall · Norfolk, VA |
| 25 | Sat Feb 15 | atMD-Eastern | W75-63 | 17-8 | .680 | - | | Hytche Athletic Center · Princess Anne, MD |
| 26 | Mon Feb 17 | vsDelaware St | W96-84 | 18-8 | .692 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 27 | Sat Feb 22 | atCoppin St | W79-63 | 19-8 | .704 | - | ESPN+ | Physical Education Complex · Baltimore, MD |
| 28 | Mon Feb 24 | vsMorgan St | W69-60 | 20-8 | .714 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 29 | Sat Mar 1 | atSC State | L88-91 | 20-9 | .690 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 30 | Mon Mar 3 | atNC Central | L87-91 (OT) | 20-10 | .667 | - | ESPN+ | McDougald-McLendon Arena · Durham, NC |
| 31 | Thu Mar 6 | atHoward | W81-69 | 21-10 | .677 | - | ESPN+ | Burr Gymnasium · Washington, D.C. |
| 32 | Wed Mar 12 | vsMD-Eastern | W77-70 | 22-10 | .688 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 33 | Fri Mar 14 | vsMorgan St | W58-55 | 23-10 | .697 | - | ESPN+ | Joseph G. Echols Hall · Norfolk, VA |
| 34 | Sat Mar 15 | vsSC State | W66-65 | 24-10 | .706 | - | ESPN2 | Joseph G. Echols Hall · Norfolk, VA |
| 35 | Fri Mar 21 | at #1Florida | L69-95 | 24-11 | .686 | #16 | TNT | O'Connell Center · Gainesville, FL |
