| 1 | Tue Nov 9 | vs Bakersfield | W95-58 | 1-0 | 1.000 | #2 | PACN | Pauley Pavilion · Los Angeles, CA |
| 2 | Fri Nov 12 | vs #4Villanova | W86-77 (OT) | 2-0 | 1.000 | #2 | ESPN2 | Pauley Pavilion · Los Angeles, CA |
| 3 | Mon Nov 15 | vs Long Beach St | W100-79 | 3-0 | 1.000 | #2 | PACN | Pauley Pavilion · Los Angeles, CA |
| 4 | Wed Nov 17 | vs North Florida | W98-63 | 4-0 | 1.000 | #2 | PACN | Pauley Pavilion · Los Angeles, CA |
| 5 | Mon Nov 22 | at Bellarmine | W75-62 | 5-0 | 1.000 | - | | Knights Hall · Louisville, KY |
| 6 | Tue Nov 23 | vs Gonzaga | L63-83 | 5-1 | .833 | - | ESPN | Pauley Pavilion · Los Angeles, CA |
| 7 | Sat Nov 27 | at UNLV | W73-51 | 6-1 | .857 | #2 | | Thomas & Mack Center · Las Vegas, NV |
| 8 | Wed Dec 1 | vs Colorado | W73-61 | 7-1 | .875 | #5 | PACN | Pauley Pavilion · Los Angeles, CA |
| 9 | Sun Dec 5 | at Washington | PPD | 7-1 | .875 | #5 | | Alaska Airlines Arena · Seattle, WA |
| 10 | Sat Dec 11 | at Marquette | W67-56 | 8-1 | .889 | #4 | FS2 | Fiserv Forum · Milwaukee, WI |
| 13 | Thu Dec 30 | vs #9Arizona | PPD | 27-8 | .771 | #5 | | Pauley Pavilion · Los Angeles, CA |
| 14 | Sat Jan 1 | vs Arizona St | PPD | 27-8 | .771 | #5 | | Pauley Pavilion · Los Angeles, CA |
| 15 | Wed Jan 5 | vsArizona St | PPD | 27-8 | .771 | #5 | | Pauley Pavilion · Los Angeles, CA |
| 16 | Thu Jan 6 | vsLong Beach St | W96-78 | 9-1 | .900 | #5 | PACN | Pauley Pavilion · Los Angeles, CA |
| 17 | Sat Jan 8 | at California | W60-52 | 10-1 | .909 | #5 | PACN | Haas Pavilion · Berkeley, CA |
| 18 | Thu Jan 13 | vs Oregon | L81-84 (OT) | 10-2 | .833 | #3 | ESPN | Pauley Pavilion · Los Angeles, CA |
| 19 | Sat Jan 15 | vs Oregon St | W81-65 | 11-2 | .846 | #3 | PACN | Pauley Pavilion · Los Angeles, CA |
| 20 | Thu Jan 20 | at Utah | W63-58 | 12-2 | .857 | #9 | FS1 | Jon M. Huntsman Center · Salt Lake City, UT |
| 21 | Sat Jan 22 | atColorado | W71-65 | 13-2 | .867 | #9 | | CU Events Center · Boulder, CO |
| 22 | Tue Jan 25 | vs#3Arizona | W75-59 | 14-2 | .875 | #7 | ESPN | Pauley Pavilion · Los Angeles, CA |
| 23 | Thu Jan 27 | vsCalifornia | W81-57 | 15-2 | .882 | #7 | PACN | Pauley Pavilion · Los Angeles, CA |
| 24 | Sat Jan 29 | vs Stanford | W66-43 | 16-2 | .889 | #7 | PACN | Pauley Pavilion · Los Angeles, CA |
| 25 | Thu Feb 3 | at#7Arizona | L66-76 | 16-3 | .842 | #3 | ESPN | McKale Center · Tucson, AZ |
| 26 | Sat Feb 5 | atArizona St | L84-87 (3OT) | 16-4 | .800 | #3 | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 27 | Tue Feb 8 | atStanford | W79-70 | 17-4 | .810 | #12 | ESPN2 | Maples Pavilion · Stanford, CA |
| 28 | Sat Feb 12 | at #21USC | L64-67 | 17-5 | .773 | #12 | ESPN | Galen Center · Los Angeles, CA |
| 29 | Thu Feb 17 | vs Washington St | W76-56 | 18-5 | .783 | #13 | FS1 | Pauley Pavilion · Los Angeles, CA |
| 30 | Sat Feb 19 | vsWashington | W76-50 | 19-5 | .792 | #13 | FS1 | Pauley Pavilion · Los Angeles, CA |
| 31 | Mon Feb 21 | vsArizona St | W66-52 | 20-5 | .800 | #12 | FS1 | Pauley Pavilion · Los Angeles, CA |
| 32 | Thu Feb 24 | atOregon | L63-68 | 20-6 | .769 | #12 | ESPN | Matthew Knight Arena · Eugene, OR |
| 33 | Sat Feb 26 | atOregon St | W94-55 | 21-6 | .778 | #12 | CBS | Gill Coliseum · Corvallis, OR |
| 34 | Mon Feb 28 | atWashington | W77-66 | 22-6 | .786 | #17 | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 35 | Sat Mar 5 | vs#16USC | W75-68 | 23-6 | .793 | #17 | ESPN | Pauley Pavilion · Los Angeles, CA |
| 36 | Thu Mar 10 | vsWashington St | W75-65 | 24-6 | .800 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 37 | Fri Mar 11 | vsUSC | W69-59 | 25-6 | .806 | - | FS1 | Pauley Pavilion · Los Angeles, CA |
| 38 | Sat Mar 12 | atArizona | L76-84 | 25-7 | .781 | - | FOX | McKale Center · Tucson, AZ |
| 39 | Thu Mar 17 | vs #13Akron | W57-53 | 26-7 | .788 | #4 | TBS | Pauley Pavilion · Los Angeles, CA |
| 40 | Sat Mar 19 | vs #5Saint Mary's | W72-56 | 27-7 | .794 | #4 | TBS | Pauley Pavilion · Los Angeles, CA |
| 41 | Fri Mar 25 | vs #8UNC | L66-73 | 27-8 | .771 | #4 | CBS | Pauley Pavilion · Los Angeles, CA |
Alabama St
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