| 1 | Wed Nov 25 | at SDSU | L58-73 | 0-1 | .000 | #22 | CBS | Viejas Arena · San Diego, CA |
| 2 | Fri Nov 27 | vs Pepperdine | W107-98 (3OT) | 1-1 | .500 | #22 | PACN | Pauley Pavilion · Los Angeles, CA |
| 4 | Thu Dec 3 | vs Seattle U | W78-52 | 2-1 | .667 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 5 | Sun Dec 6 | vs California | W76-56 | 3-1 | .750 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 6 | Wed Dec 9 | vs San Diego | W83-56 | 4-1 | .800 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 7 | Fri Dec 11 | vs Marquette | W69-60 | 5-1 | .833 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 9 | Sat Dec 19 | at Ohio State | L70-77 | 5-2 | .714 | - | CBS | Value City Arena · Columbus, OH |
| 10 | Wed Dec 23 | at #25Oregon | PPD | 22-10 | .688 | - | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 11 | Thu Dec 31 | vs Utah | W72-70 | 6-2 | .750 | - | FS1 | Pauley Pavilion · Los Angeles, CA |
| 12 | Sat Jan 2 | vs Colorado | W65-62 | 7-2 | .778 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 13 | Thu Jan 7 | at Arizona St | W81-75 (OT) | 8-2 | .800 | - | ESPN | Desert Financial Arena · Tempe, AZ |
| 14 | Sat Jan 9 | at Arizona | W81-76 | 9-2 | .818 | - | ESPN | McKale Center · Tucson, AZ |
| 15 | Thu Jan 14 | vs Washington St | W91-61 | 10-2 | .833 | - | FS1 | Pauley Pavilion · Los Angeles, CA |
| 16 | Sat Jan 16 | vs Washington | W81-76 | 11-2 | .846 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 17 | Tue Jan 19 | at#21Oregon | PPD | 22-10 | .688 | #24 | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 18 | Thu Jan 21 | atCalifornia | W61-57 | 12-2 | .857 | #24 | ESPNU | Haas Pavilion · Berkeley, CA |
| 19 | Sat Jan 23 | at Stanford | L72-73 (OT) | 12-3 | .800 | #24 | FOX | Maples Pavilion · Stanford, CA |
| 21 | Sat Jan 30 | vs Oregon St | W57-52 | 13-3 | .813 | #23 | PACN | Pauley Pavilion · Los Angeles, CA |
| 23 | Sat Feb 6 | at USC | L48-66 | 13-4 | .765 | - | ESPN | Galen Center · Los Angeles, CA |
| 24 | Thu Feb 11 | atWashington St | L73-81 | 13-5 | .722 | - | FS1 | Friel Court at Beasley Coliseum · Pullman, WA |
| 25 | Sat Feb 13 | atWashington | W64-61 | 14-5 | .737 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 26 | Thu Feb 18 | vsArizona | W74-60 | 15-5 | .750 | - | ESPN2 | Pauley Pavilion · Los Angeles, CA |
| 27 | Sat Feb 20 | vsArizona St | W80-79 | 16-5 | .762 | - | ESPN2 | Pauley Pavilion · Los Angeles, CA |
| 28 | Thu Feb 25 | atUtah | W76-61 | 17-5 | .773 | - | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 29 | Sat Feb 27 | atColorado | L61-70 | 17-6 | .739 | - | ESPN2 | CU Events Center · Boulder, CO |
| 30 | Wed Mar 3 | atOregon | L74-82 | 17-7 | .708 | - | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 31 | Sat Mar 6 | vsUSC | L63-64 | 17-8 | .680 | - | CBS | Pauley Pavilion · Los Angeles, CA |
| 32 | Thu Mar 11 | vsOregon St | L79-83 (OT) | 17-9 | .654 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 33 | Thu Mar 18 | at #11Michigan St | W86-80 (OT) | 18-9 | .667 | #11 | TBS | Breslin Center · East Lansing, MI |
| 34 | Sat Mar 20 | at #6BYU | W73-62 | 19-9 | .679 | #11 | CBS | Marriott Center · Provo, UT |
| 35 | Mon Mar 22 | vs #14Abilene Chrstn | W67-47 | 20-9 | .690 | #11 | TBS | Pauley Pavilion · Los Angeles, CA |
| 36 | Sun Mar 28 | at #2Alabama | W88-78 (OT) | 21-9 | .700 | #11 | TBS | Coleman Coliseum · Tuscaloosa, AL |
| 37 | Tue Mar 30 | at #1Michigan | W51-49 | 22-9 | .710 | #11 | TBS | Crisler Center · Ann Arbor, MI |
| 38 | Sat Apr 3 | at #1Gonzaga | L90-93 (OT) | 22-10 | .688 | #11 | CBS | McCarthey Athletic Center · Spokane, WA |
Long Beach St