| 1 | Mon Nov 7 | vs FGCU | L61-74 | 0-1 | .000 | - | | Galen Center · Los Angeles, CA |
| 2 | Thu Nov 10 | vs Alabama St | W96-58 | 1-1 | .500 | - | PACN | Galen Center · Los Angeles, CA |
| 3 | Tue Nov 15 | vs Vermont | W59-57 | 2-1 | .667 | - | PACN | Galen Center · Los Angeles, CA |
| 4 | Fri Nov 18 | vs Mount St Mary | W83-74 | 3-1 | .750 | - | PACN | Galen Center · Los Angeles, CA |
| 5 | Wed Nov 23 | vs BYU | W82-76 | 4-1 | .800 | - | ESPN2 | Galen Center · Los Angeles, CA |
| 6 | Thu Nov 24 | vs Tennessee | L66-73 (OT) | 4-2 | .667 | - | ESPN2 | Galen Center · Los Angeles, CA |
| 7 | Fri Nov 25 | at Wisconsin | L59-64 | 4-3 | .571 | - | ESPN2 | Kohl Center · Madison, WI |
| 8 | Wed Nov 30 | at California | W66-51 | 5-3 | .625 | - | PACN | Haas Pavilion · Berkeley, CA |
| 9 | Sun Dec 4 | vs Oregon St | W63-62 | 6-3 | .667 | - | PACN | Galen Center · Los Angeles, CA |
| 10 | Wed Dec 7 | vs Fullerton | W64-50 | 7-3 | .700 | - | PACN | Galen Center · Los Angeles, CA |
| 11 | Wed Dec 14 | vs Long Beach St | W88-78 | 8-3 | .727 | - | PACN | Galen Center · Los Angeles, CA |
| 12 | Sun Dec 18 | vs #19Auburn | W74-71 | 9-3 | .750 | - | ESPN | Galen Center · Los Angeles, CA |
| 13 | Wed Dec 21 | vs Colorado St | W73-64 | 10-3 | .769 | - | PACN | Galen Center · Los Angeles, CA |
| 14 | Fri Dec 30 | at Washington | W80-67 | 11-3 | .786 | - | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 15 | Sun Jan 1 | at Washington St | L71-81 | 11-4 | .733 | - | PACN | Friel Court at Beasley Coliseum · Pullman, WA |
| 16 | Thu Jan 5 | at #10UCLA | L58-60 | 11-5 | .688 | - | ESPN | Pauley Pavilion · Los Angeles, CA |
| 17 | Thu Jan 12 | vs Colorado | W68-61 | 12-5 | .706 | - | PACN | Galen Center · Los Angeles, CA |
| 18 | Sat Jan 14 | vs Utah | W71-56 | 13-5 | .722 | - | PACN | Galen Center · Los Angeles, CA |
| 19 | Thu Jan 19 | at #11Arizona | L66-81 | 13-6 | .684 | - | PACN | McKale Center · Tucson, AZ |
| 20 | Sat Jan 21 | at Arizona St | W77-69 | 14-6 | .700 | - | ESPNU | Desert Financial Arena · Tempe, AZ |
| 21 | Thu Jan 26 | vs#8UCLA | W77-64 | 15-6 | .714 | - | ESPN2 | Galen Center · Los Angeles, CA |
| 22 | Thu Feb 2 | vsWashington St | W80-70 | 16-6 | .727 | - | FS1 | Galen Center · Los Angeles, CA |
| 23 | Sat Feb 4 | vsWashington | W80-74 | 17-6 | .739 | - | FS1 | Galen Center · Los Angeles, CA |
| 24 | Thu Feb 9 | at Oregon | L60-78 | 17-7 | .708 | - | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 25 | Sat Feb 11 | atOregon St | L58-61 | 17-8 | .680 | - | PACN | Gill Coliseum · Corvallis, OR |
| 26 | Thu Feb 16 | vsCalifornia | W97-60 | 18-8 | .692 | - | FS1 | Galen Center · Los Angeles, CA |
| 27 | Sat Feb 18 | vs Stanford | W85-75 | 19-8 | .704 | - | ESPNU | Galen Center · Los Angeles, CA |
| 28 | Thu Feb 23 | atColorado | W84-65 | 20-8 | .714 | - | ESPN2 | CU Events Center · Boulder, CO |
| 29 | Sat Feb 25 | atUtah | W62-49 | 21-8 | .724 | - | ESPNU | Jon M. Huntsman Center · Salt Lake City, UT |
| 30 | Thu Mar 2 | vs#8Arizona | L81-87 | 21-9 | .700 | - | ESPN | Galen Center · Los Angeles, CA |
| 31 | Sat Mar 4 | vsArizona St | W68-65 | 22-9 | .710 | - | FS1 | Galen Center · Los Angeles, CA |
| 32 | Thu Mar 9 | vsArizona St | L72-77 | 22-10 | .688 | - | ESPN | Galen Center · Los Angeles, CA |
| 33 | Fri Mar 17 | at #7Michigan St | L62-72 | 22-11 | .667 | #10 | CBS | Breslin Center · East Lansing, MI |
