| 1 | Mon Nov 3 | at Miami | L69-86 | 0-1 | .000 | - | ACC Extra | Watsco Center · Coral Gables, FL |
| 2 | Thu Nov 6 | vsTBD | W132-45 | 1-1 | .500 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 3 | Tue Nov 11 | atHigh Point | L64-85 | 1-2 | .333 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 4 | Sat Nov 15 | atVMI | W69-67 | 2-2 | .500 | - | ESPN+ | Cameron Hall · Lexington, VA |
| 5 | Tue Nov 18 | atGeorge Mason | L57-79 | 2-3 | .400 | - | ESPN+ | EagleBank Arena · Fairfax, VA |
| 6 | Mon Nov 24 | atBethune | W69-64 | 3-3 | .500 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
| 7 | Tue Nov 25 | vsPacific | L53-68 | 3-4 | .429 | - | | Swisher Gymnasium · Jacksonville, FL |
| 8 | Tue Dec 2 | vsFAMU | W85-82 (OT) | 4-4 | .500 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 9 | Sat Dec 6 | atFIU | L65-88 | 4-5 | .444 | - | ESPN+ | Ocean Bank Convocation Center · Miami, FL |
| 10 | Thu Dec 11 | vsTBD | W122-49 | 5-5 | .500 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 11 | Sun Dec 14 | atTexas A&M | L75-112 | 5-6 | .455 | - | SEC Network | Reed Arena · College Station, TX |
| 12 | Wed Dec 17 | atFAMU | L65-72 | 5-7 | .417 | - | | Al Lawson Center · Tallahassee, FL |
| 13 | Mon Dec 22 | atFlorida St | L63-87 | 5-8 | .385 | - | ACC Extra | Donald L. Tucker Center · Tallahassee, FL |
| 14 | Thu Jan 1 | atLipscomb | L57-76 | 5-9 | .357 | - | ESPN+ | Allen Arena · Nashville, TN |
| 15 | Sat Jan 3 | atAustin Peay | L68-71 | 5-10 | .333 | - | ESPN+ | Winfield Dunn Center · Clarksville, TN |
| 16 | Thu Jan 8 | vsQueens | L51-77 | 5-11 | .313 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 17 | Sat Jan 10 | vsW Georgia | W75-43 | 6-11 | .353 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 18 | Thu Jan 15 | atC Arkansas | L60-62 | 6-12 | .333 | - | ESPN+ | Farris Center · Conway, AR |
| 19 | Sat Jan 17 | atNorth Alabama | W90-68 | 7-12 | .368 | - | ESPN+ | Flowers Hall · Florence, AL |
| 20 | Thu Jan 22 | vsBellarmine | L70-77 | 7-13 | .350 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 21 | Sat Jan 24 | vsE Kentucky | W81-76 (OT) | 8-13 | .381 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 22 | Thu Jan 29 | vsLipscomb | W70-65 | 9-13 | .409 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 23 | Sat Jan 31 | vsFGCU | L49-68 | 9-14 | .391 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 24 | Thu Feb 5 | atQueens | L84-93 | 9-15 | .375 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 25 | Sat Feb 7 | atW Georgia | L73-87 | 9-16 | .360 | - | ESPN+ | The Coliseum · Carrollton, GA |
| 26 | Wed Feb 11 | atStetson | L62-67 | 9-17 | .346 | - | ESPN+ | Edmunds Center · Deland, FL |
| 27 | Sat Feb 14 | vsNorth Florida | W63-56 | 10-17 | .370 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 28 | Wed Feb 18 | atFGCU | L84-86 | 10-18 | .357 | - | ESPN+ | Alico Arena · Fort Myers, FL |
| 29 | Sat Feb 21 | vsAustin Peay | L61-65 | 10-19 | .345 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 30 | Thu Feb 26 | vsStetson | W89-85 | 11-19 | .367 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 31 | Sat Feb 28 | atNorth Florida | W85-61 | 12-19 | .387 | - | ESPN+ | UNF Arena · Jacksonville, FL |
