| 1 | Tue Nov 9 | vs TBD | W79-43 | 1-0 | 1.000 | - | | Swisher Gymnasium · Jacksonville, FL |
| 2 | Sat Nov 13 | vsNC A&T | W63-54 | 2-0 | 1.000 | - | | Swisher Gymnasium · Jacksonville, FL |
| 3 | Tue Nov 16 | atUCF | L54-63 | 2-1 | .667 | - | | Addition Financial Arena · Orlando, FL |
| 4 | Wed Nov 24 | atMinnesota | L44-55 | 2-2 | .500 | - | BTN | Williams Arena · Minneapolis, MN |
| 5 | Sat Nov 27 | vsTBD | W83-54 | 3-2 | .600 | - | | Swisher Gymnasium · Jacksonville, FL |
| 6 | Thu Dec 2 | atCharleston So | W67-56 | 4-2 | .667 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 7 | Tue Dec 7 | atGeorgia | L58-69 | 4-3 | .571 | - | | Stegeman Coliseum · Athens, GA |
| 8 | Sat Dec 11 | vsUNC Wilmington | W77-48 | 5-3 | .625 | - | | Swisher Gymnasium · Jacksonville, FL |
| 9 | Tue Dec 14 | atSouthern Miss | W62-51 | 6-3 | .667 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 10 | Sat Dec 18 | vsTBD | W87-48 | 7-3 | .700 | - | | Swisher Gymnasium · Jacksonville, FL |
| 11 | Tue Dec 21 | atPitt | L55-64 | 7-4 | .636 | - | ACC Network | Petersen Events Center · Pittsburgh, PA |
| 12 | Wed Dec 29 | vsTBD | W98-45 | 8-4 | .667 | - | | Swisher Gymnasium · Jacksonville, FL |
| 14 | Wed Jan 5 | atKennesaw St | PPD | 21-10 | .677 | - | | KSU Convocation Center · Kennesaw, GA |
| 15 | Sat Jan 8 | vsFGCU | W69-66 | 9-4 | .692 | - | | Swisher Gymnasium · Jacksonville, FL |
| 16 | Tue Jan 11 | vsStetson | W57-50 | 10-4 | .714 | - | | Swisher Gymnasium · Jacksonville, FL |
| 17 | Sat Jan 15 | atNorth Florida | W54-51 | 11-4 | .733 | - | | UNF Arena · Jacksonville, FL |
| 18 | Tue Jan 18 | atLiberty | L49-88 | 11-5 | .688 | - | | Liberty Arena · Lynchburg, VA |
| 19 | Sat Jan 22 | atBellarmine | L73-76 (OT) | 11-6 | .647 | - | | Knights Hall · Louisville, KY |
| 20 | Mon Jan 24 | atKennesaw St | L68-76 | 11-7 | .611 | - | | KSU Convocation Center · Kennesaw, GA |
| 21 | Thu Jan 27 | vsLipscomb | W66-59 | 12-7 | .632 | - | | Swisher Gymnasium · Jacksonville, FL |
| 22 | Sat Jan 29 | vsC Arkansas | W79-59 | 13-7 | .650 | - | | Swisher Gymnasium · Jacksonville, FL |
| 23 | Thu Feb 3 | atNorth Alabama | W56-50 | 14-7 | .667 | - | | Flowers Hall · Florence, AL |
| 24 | Sat Feb 5 | atJ'Ville St | L58-64 | 14-8 | .636 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 25 | Wed Feb 9 | vsE Kentucky | W81-68 | 15-8 | .652 | - | | Swisher Gymnasium · Jacksonville, FL |
| 26 | Sat Feb 12 | vsLiberty | W73-69 | 16-8 | .667 | - | | Swisher Gymnasium · Jacksonville, FL |
| 27 | Wed Feb 16 | atStetson | W67-45 | 17-8 | .680 | - | | Edmunds Center · Deland, FL |
| 28 | Sat Feb 19 | vsKennesaw St | W59-56 | 18-8 | .692 | - | | Swisher Gymnasium · Jacksonville, FL |
| 29 | Wed Feb 23 | vsNorth Florida | W71-39 | 19-8 | .704 | - | | Swisher Gymnasium · Jacksonville, FL |
| 30 | Sat Feb 26 | atFGCU | L69-76 | 19-9 | .679 | - | | Alico Arena · Fort Myers, FL |
| 31 | Thu Mar 3 | vsC Arkansas | W79-69 | 20-9 | .690 | - | | Swisher Gymnasium · Jacksonville, FL |
| 32 | Sat Mar 5 | atJ'Ville St | W54-51 | 21-9 | .700 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 33 | Tue Mar 8 | atBellarmine | L72-77 | 21-10 | .677 | - | ESPN2 | Knights Hall · Louisville, KY |
