| 1 | Mon Nov 4 | at #12Tennessee | L64-80 | 0-1 | .000 | - | ESPN+ | Thompson-Boling Arena · Knoxville, TN |
| 2 | Fri Nov 8 | at NC Central | W88-82 | 1-1 | .500 | - | | McDougald-McLendon Arena · Durham, NC |
| 3 | Mon Nov 11 | at Pitt | L64-83 | 1-2 | .333 | - | ESPN+ | Petersen Events Center · Pittsburgh, PA |
| 4 | Fri Nov 15 | vs Elon | W80-79 | 2-2 | .500 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 5 | Tue Nov 19 | at Charlotte | L54-60 | 2-3 | .400 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 6 | Tue Nov 26 | vs SE Louisiana | W73-69 | 3-3 | .500 | - | | Paul Porter Arena · Boiling Springs, NC |
| 7 | Wed Nov 27 | at Bethune | W79-64 | 4-3 | .571 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
| 8 | Fri Nov 29 | at Belmont | L74-83 | 4-4 | .500 | - | ESPN+ | Curb Event Center Arena · Nashville, TN |
| 9 | Wed Dec 4 | at Wofford | L64-88 | 4-5 | .444 | - | ESPN+ | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 10 | Sat Dec 7 | vsNC Central | L77-78 | 4-6 | .400 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 11 | Sat Dec 14 | vs Queens | L83-85 | 4-7 | .364 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 12 | Tue Dec 17 | at Georgia So | L81-86 | 4-8 | .333 | - | ESPN+ | W.S. Hanner Fieldhouse · Statesboro, GA |
| 13 | Sat Dec 21 | at E Carolina | W84-79 | 5-8 | .385 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 14 | Thu Jan 2 | at Charleston So | L63-72 | 5-9 | .357 | - | ESPN+ | Buccaneer Fieldhouse · Charleston, SC |
| 15 | Sat Jan 4 | vs Presbyterian | W63-61 | 6-9 | .400 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 16 | Wed Jan 8 | vs Winthrop | W89-83 | 7-9 | .438 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 17 | Sat Jan 11 | at High Point | L55-96 | 7-10 | .412 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 18 | Wed Jan 15 | at Radford | L75-79 | 7-11 | .389 | - | ESPN+ | Donald N. Dedmon Center · Radford, VA |
| 19 | Sat Jan 18 | vs SC Upstate | W97-68 | 8-11 | .421 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 20 | Wed Jan 22 | vs UNC Asheville | L53-61 | 8-12 | .400 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 21 | Wed Jan 29 | vs Longwood | W92-87 | 9-12 | .429 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 22 | Sat Feb 1 | atWinthrop | L93-96 | 9-13 | .409 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 23 | Thu Feb 6 | atUNC Asheville | L70-78 | 9-14 | .391 | - | ESPNU | Kimmel Arena · Asheville, NC |
| 24 | Sat Feb 8 | vsCharleston So | L72-79 | 9-15 | .375 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 25 | Sat Feb 15 | atSC Upstate | W96-87 | 10-15 | .400 | - | ESPN+ | G.B. Hodge Center · Spartanburg, SC |
| 26 | Wed Feb 19 | atLongwood | L77-90 | 10-16 | .385 | - | ESPN+ | Willett Hall · Farmville, VA |
