| 1 | Mon Nov 4 | vs TBD | W79-68 | 1-0 | 1.000 | - | ESPN+ | Willett Hall · Farmville, VA |
| 2 | Sat Nov 9 | vs Morgan St | W84-66 | 2-0 | 1.000 | - | ESPN+ | Willett Hall · Farmville, VA |
| 3 | Wed Nov 13 | vs Milwaukee | W76-62 | 3-0 | 1.000 | - | ESPN+ | Willett Hall · Farmville, VA |
| 4 | Sat Nov 16 | vs UT Martin | W64-62 | 4-0 | 1.000 | - | ESPN+ | Willett Hall · Farmville, VA |
| 5 | Tue Nov 19 | at Binghamton | W66-60 | 5-0 | 1.000 | - | ESPN+ | Events Center (Binghamton) · Binghamton, NY |
| 6 | Fri Nov 22 | at UAB | W89-81 | 6-0 | 1.000 | - | ESPN+ | Bartow Arena · Birmingham, AL |
| 7 | Sun Nov 24 | at McNeese | L69-84 | 6-1 | .857 | - | ESPN+ | Legacy Center · Lake Charles, LA |
| 8 | Mon Nov 25 | at Kansas St | L64-80 | 6-2 | .750 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 9 | Sun Dec 1 | vsTBD | W108-55 | 7-2 | .778 | - | ESPN+ | Willett Hall · Farmville, VA |
| 10 | Thu Dec 5 | vs MD-Eastern | W80-76 | 8-2 | .800 | - | ESPN+ | Willett Hall · Farmville, VA |
| 11 | Sun Dec 8 | vsTBD | W97-40 | 9-2 | .818 | - | ESPN+ | Willett Hall · Farmville, VA |
| 12 | Sat Dec 14 | vs NC Central | L70-77 | 9-3 | .750 | - | ESPN+ | Willett Hall · Farmville, VA |
| 13 | Wed Dec 18 | at Campbell | W77-55 | 10-3 | .769 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 14 | Fri Dec 20 | atNC Central | W82-67 | 11-3 | .786 | - | ESPN+ | McDougald-McLendon Arena · Durham, NC |
| 15 | Sun Dec 29 | at SMU | L82-98 | 11-4 | .733 | - | ESPN+ | Moody Coliseum · Dallas, TX |
| 16 | Thu Jan 2 | at Presbyterian | L60-68 | 11-5 | .688 | - | ESPN+ | Ross E. Templeton P.E. Center · Clinton, SC |
| 17 | Sat Jan 4 | vs Charleston So | W83-78 | 12-5 | .706 | - | ESPN+ | Willett Hall · Farmville, VA |
| 18 | Wed Jan 8 | vs UNC Asheville | W85-76 | 13-5 | .722 | - | ESPN+ | Willett Hall · Farmville, VA |
| 19 | Sat Jan 11 | at Winthrop | L76-95 | 13-6 | .684 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 20 | Thu Jan 16 | vs High Point | W82-80 | 14-6 | .700 | - | ESPNU | Willett Hall · Farmville, VA |
| 21 | Wed Jan 22 | at Radford | W77-74 | 15-6 | .714 | - | ESPN+ | Donald N. Dedmon Center · Radford, VA |
| 22 | Sat Jan 25 | vs SC Upstate | W80-54 | 16-6 | .727 | - | ESPN+ | Willett Hall · Farmville, VA |
| 23 | Wed Jan 29 | at Gardner-Webb | L87-92 | 16-7 | .696 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 24 | Sat Feb 1 | atCharleston So | L85-89 | 16-8 | .667 | - | ESPN+ | Buccaneer Fieldhouse · Charleston, SC |
| 25 | Sat Feb 8 | vsRadford | L69-71 | 16-9 | .640 | - | ESPN+ | Willett Hall · Farmville, VA |
| 26 | Thu Feb 13 | atHigh Point | L72-83 | 16-10 | .615 | - | ESPNU | Nido and Mariana Qubein Arena · High Point, NC |
| 27 | Sat Feb 15 | vsPresbyterian | L68-77 | 16-11 | .593 | - | ESPN+ | Willett Hall · Farmville, VA |
| 28 | Wed Feb 19 | vsGardner-Webb | W90-77 | 17-11 | .607 | - | ESPN+ | Willett Hall · Farmville, VA |
| 29 | Sat Feb 22 | atUNC Asheville | L82-87 | 17-12 | .586 | - | ESPN+ | Kimmel Arena · Asheville, NC |
| 30 | Thu Feb 27 | vsWinthrop | L59-85 | 17-13 | .567 | - | ESPNU | Willett Hall · Farmville, VA |
| 31 | Sat Mar 1 | atSC Upstate | W83-66 | 18-13 | .581 | - | ESPN+ | G.B. Hodge Center · Spartanburg, SC |
| 32 | Fri Mar 7 | atWinthrop | L79-88 | 18-14 | .563 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
