| 1 | Mon Nov 6 | at St Bonaventure | L69-73 | 0-1 | .000 | - | | Reilly Center · Saint Bonaventure, NY |
| 2 | Sat Nov 11 | vsTBD | W95-43 | 1-1 | .500 | - | | Willett Hall · Farmville, VA |
| 3 | Wed Nov 15 | atMD-Eastern | W80-61 | 2-1 | .667 | - | | Hytche Athletic Center · Princess Anne, MD |
| 4 | Sat Nov 18 | vsNC Central | W73-66 | 3-1 | .750 | - | | Willett Hall · Farmville, VA |
| 5 | Fri Nov 24 | vsDelaware St | W84-82 (2OT) | 4-1 | .800 | - | | Willett Hall · Farmville, VA |
| 6 | Sat Nov 25 | vsLamar | W83-72 | 5-1 | .833 | - | | Willett Hall · Farmville, VA |
| 7 | Sun Nov 26 | vsBethune | W69-48 | 6-1 | .857 | - | | Willett Hall · Farmville, VA |
| 8 | Thu Nov 30 | vsTBD | W95-46 | 7-1 | .875 | - | | Willett Hall · Farmville, VA |
| 9 | Sun Dec 3 | atMorgan St | W88-54 | 8-1 | .889 | - | | Hill Field House · Baltimore, MD |
| 10 | Sat Dec 9 | atDelaware St | W62-61 | 9-1 | .900 | - | | Memorial Hall (Dover, DE) · Dover, DE |
| 11 | Mon Dec 11 | vsTBD | W92-61 | 10-1 | .909 | - | | Willett Hall · Farmville, VA |
| 12 | Wed Dec 13 | atMilwaukee | W80-67 | 11-1 | .917 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 13 | Sun Dec 17 | vsVMI | W68-49 | 12-1 | .923 | - | | Willett Hall · Farmville, VA |
| 14 | Wed Dec 20 | atNC Central | L70-79 | 12-2 | .857 | - | | McDougald-McLendon Arena · Durham, NC |
| 15 | Sat Dec 30 | atDayton | L69-78 | 12-3 | .800 | - | | UD Arena · Dayton, OH |
| 16 | Wed Jan 3 | atWinthrop | L60-68 (OT) | 12-4 | .750 | - | | Winthrop Coliseum · Rock Hill, SC |
| 17 | Sat Jan 6 | vsCharleston So | W77-56 | 13-4 | .765 | - | | Willett Hall · Farmville, VA |
| 18 | Thu Jan 11 | vsRadford | L58-69 | 13-5 | .722 | - | ESPNU | Willett Hall · Farmville, VA |
| 19 | Sat Jan 13 | atUNC Asheville | L61-65 | 13-6 | .684 | - | | Kimmel Arena · Asheville, NC |
| 20 | Wed Jan 17 | atSC Upstate | L71-73 | 13-7 | .650 | - | | G.B. Hodge Center · Spartanburg, SC |
| 21 | Sat Jan 20 | vsPresbyterian | W80-70 | 14-7 | .667 | - | | Willett Hall · Farmville, VA |
| 22 | Wed Jan 24 | vsGardner-Webb | L64-76 | 14-8 | .636 | - | | Willett Hall · Farmville, VA |
| 23 | Thu Feb 1 | atHigh Point | L76-93 | 14-9 | .609 | - | ESPNU | Nido and Mariana Qubein Arena · High Point, NC |
| 24 | Sat Feb 3 | atCharleston So | L77-83 | 14-10 | .583 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 25 | Wed Feb 7 | vsSC Upstate | L64-69 | 14-11 | .560 | - | | Willett Hall · Farmville, VA |
| 26 | Sat Feb 10 | vsWinthrop | W84-74 | 15-11 | .577 | - | | Willett Hall · Farmville, VA |
| 27 | Sat Feb 17 | atPresbyterian | W81-73 | 16-11 | .593 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 28 | Wed Feb 21 | vsUNC Asheville | W80-75 | 17-11 | .607 | - | | Willett Hall · Farmville, VA |
| 29 | Sat Feb 24 | atRadford | L82-88 | 17-12 | .586 | - | | Donald N. Dedmon Center · Radford, VA |
| 30 | Thu Feb 29 | atGardner-Webb | L69-72 | 17-13 | .567 | - | ESPNU | Paul Porter Arena · Boiling Springs, NC |
| 31 | Sat Mar 2 | vsHigh Point | W74-72 | 18-13 | .581 | - | | Willett Hall · Farmville, VA |
| 32 | Fri Mar 8 | atWinthrop | W69-56 | 19-13 | .594 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 33 | Sat Mar 9 | atHigh Point | W80-79 (OT) | 20-13 | .606 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 34 | Sun Mar 10 | atUNC Asheville | W85-59 | 21-13 | .618 | - | ESPN2 | Nido and Mariana Qubein Arena · High Point, NC |
| 35 | Fri Mar 22 | at#1Houston | L46-86 | 21-14 | .600 | #16 | TNT | FedExForum · Memphis, TN |
