| 1 | Tue Dec 1 | vs TBD | W102-57 | 1-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 2 | Fri Dec 4 | vsMcNeese | W86-76 | 2-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 3 | Sun Dec 6 | vsTBD | W97-79 | 3-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 4 | Wed Dec 9 | atBaylor | L52-83 | 3-1 | .750 | - | | Ferrell Center · Waco, TX |
| 5 | Sat Dec 12 | atUL Monroe | L55-66 | 3-2 | .600 | - | | Fant-Ewing Coliseum · Monroe, LA |
| 9 | Sat Jan 2 | vsNew Orleans | W78-67 | 4-2 | .667 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 10 | Fri Jan 8 | vsTBD | W87-71 | 5-2 | .714 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 11 | Wed Jan 13 | vsC Arkansas | W95-69 | 6-2 | .750 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 12 | Sat Jan 16 | atIncarnate Word | W83-65 | 7-2 | .778 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 13 | Wed Jan 20 | vsN'Western St | W86-74 | 8-2 | .800 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 14 | Sat Jan 23 | vsLamar | W102-72 | 9-2 | .818 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 15 | Wed Jan 27 | atAbilene Chrstn | L62-82 | 9-3 | .750 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 16 | Sun Jan 31 | vsSam Houston | W78-68 | 10-3 | .769 | - | ESPNU | William R. Johnson Coliseum · Nacogdoches, TX |
| 17 | Wed Feb 3 | atTexas A&M-CC | W84-75 | 11-3 | .786 | - | | American Bank Center · Corpus Christi, TX |
| 18 | Sat Feb 6 | atNew Orleans | PPD | 16-5 | .762 | - | | Lakefront Arena · New Orleans, LA |
| 19 | Wed Feb 10 | vsTexas A&M-CC | W80-68 | 12-3 | .800 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 20 | Mon Feb 15 | atNew Orleans | W89-79 | 13-3 | .813 | - | | Lakefront Arena · New Orleans, LA |
| 22 | Wed Feb 24 | atN'Western St | W83-57 | 14-3 | .824 | - | | Prather Coliseum · Natchitoches, LA |
| 23 | Sat Feb 27 | atLamar | L83-88 (2OT) | 14-4 | .778 | - | | Montagne Center · Beaumont, TX |
| 24 | Mon Mar 1 | atC Arkansas | W79-66 | 15-4 | .789 | - | | Farris Center · Conway, AR |
| 25 | Wed Mar 3 | vsAbilene Chrstn | L61-63 | 15-5 | .750 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 26 | Sat Mar 6 | atSam Houston | W64-59 | 16-5 | .762 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
