| 1 | Tue Nov 9 | vs TBD | W82-73 | 1-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 2 | Thu Nov 11 | vsTBD | W76-63 | 2-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 3 | Sun Nov 14 | vs S Dakota St | L71-83 | 2-1 | .667 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 4 | Fri Nov 19 | vs MTSU | W87-74 | 3-1 | .750 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 5 | Tue Nov 23 | at Buffalo | W79-78 | 4-1 | .800 | - | CBS | Alumni Arena · Buffalo, NY |
| 6 | Wed Nov 24 | at Saint Louis | L68-79 | 4-2 | .667 | - | | Chaifetz Arena · St. Louis, MO |
| 7 | Sun Nov 28 | at N'Western St | W72-68 | 5-2 | .714 | - | | Prather Coliseum · Natchitoches, LA |
| 8 | Wed Dec 1 | vsTBD | W90-54 | 6-2 | .750 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 9 | Sat Dec 4 | vsTBD | W100-76 | 7-2 | .778 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 10 | Sat Dec 11 | vs Liberty | W63-51 | 8-2 | .800 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 11 | Tue Dec 14 | vs UL Monroe | L69-82 | 8-3 | .727 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 12 | Sat Dec 18 | at #7Kansas | L72-80 | 8-4 | .667 | - | | Allen Fieldhouse · Lawrence, KS |
| 14 | Thu Dec 30 | vs UT Rio Grande | PPD | 22-10 | .688 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 15 | Thu Jan 6 | at Abilene Chrstn | W64-58 | 9-4 | .692 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 16 | Sat Jan 8 | at Tarleton | L71-77 (OT) | 9-5 | .643 | - | | placeholder · sf, ca |
| 17 | Tue Jan 11 | vsUT Rio Grande | W86-75 | 10-5 | .667 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 18 | Sat Jan 15 | at Sam Houston | L41-49 | 10-6 | .625 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 19 | Mon Jan 17 | vs Lamar | W86-78 | 11-6 | .647 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 20 | Thu Jan 20 | vs Grand Canyon | W71-46 | 12-6 | .667 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 21 | Sat Jan 22 | vs New Mexico St | L58-72 | 12-7 | .632 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 22 | Wed Jan 26 | at Seattle U | L62-70 | 12-8 | .600 | - | | Redhawk Center · Seattle, WA |
| 23 | Sat Jan 29 | at CA Baptist | W81-77 | 13-8 | .619 | - | | CBU Events Center · Riverside, CA |
| 24 | Thu Feb 3 | vs Utah Valley | W78-59 | 14-8 | .636 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 25 | Sat Feb 5 | vs Utah Tech | W81-52 | 15-8 | .652 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 26 | Thu Feb 10 | at Chicago St | W81-61 | 16-8 | .667 | - | | Jones Convocation Center · Chicago, IL |
| 27 | Wed Feb 16 | vsChicago St | W88-71 | 17-8 | .680 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 28 | Sat Feb 19 | atLamar | W70-56 | 18-8 | .692 | - | | Montagne Center · Beaumont, TX |
| 29 | Thu Feb 24 | vsSam Houston | W69-67 | 19-8 | .704 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 30 | Sat Feb 26 | vsAbilene Chrstn | W73-71 | 20-8 | .714 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 31 | Wed Mar 2 | atNew Mexico St | W73-71 | 21-8 | .724 | - | | Pan American Center · Las Cruces, NM |
| 32 | Sat Mar 5 | atUT Rio Grande | W93-63 | 22-8 | .733 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 33 | Thu Mar 10 | vsAbilene Chrstn | L62-76 | 22-9 | .710 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 34 | Sat Mar 19 | at UNC Asheville | L68-80 | 22-10 | .688 | - | | Kimmel Arena · Asheville, NC |
Jackson St