| 1 | Wed Nov 6 | vs TBD | W89-70 | 1-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 2 | Sat Nov 9 | vs NC Central | W94-64 | 2-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 3 | Wed Nov 13 | vs Niagara | W89-80 | 3-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 4 | Sat Nov 16 | vs Drexel | W82-67 | 4-0 | 1.000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 5 | Wed Nov 20 | at Rutgers | L57-69 | 4-1 | .800 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 6 | Tue Nov 26 | at #1Duke | W85-83 (OT) | 5-1 | .833 | - | | Cameron Indoor Stadium · Durham, NC |
| 7 | Sat Nov 30 | at Arkansas St | W76-57 | 6-1 | .857 | - | | First National Bank Arena · Jonesboro, AR |
| 8 | Mon Dec 2 | vsTBD | W114-49 | 7-1 | .875 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 9 | Fri Dec 6 | at Alabama | L68-78 | 7-2 | .778 | - | | Coleman Coliseum · Tuscaloosa, AL |
| 10 | Sat Dec 14 | vs UL Monroe | W66-59 | 8-2 | .800 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 11 | Wed Dec 18 | vs Hou Christian | W96-68 | 9-2 | .818 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 12 | Sat Dec 21 | at McNeese | W81-73 | 10-2 | .833 | - | | Legacy Center · Lake Charles, LA |
| 13 | Sat Dec 28 | vsTBD | W94-62 | 11-2 | .846 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 14 | Thu Jan 2 | at SE Louisiana | W82-71 | 12-2 | .857 | - | | University Center (LA) · Hammond, LA |
| 15 | Sat Jan 4 | at New Orleans | W87-68 | 13-2 | .867 | - | | Lakefront Arena · New Orleans, LA |
| 16 | Wed Jan 8 | vs Texas A&M-CC | L72-73 | 13-3 | .813 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 17 | Wed Jan 15 | at C Arkansas | W77-76 | 14-3 | .824 | - | | Farris Center · Conway, AR |
| 18 | Sat Jan 18 | vs Incarnate Word | W80-56 | 15-3 | .833 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 19 | Wed Jan 22 | at N'Western St | W69-62 | 16-3 | .842 | - | | Prather Coliseum · Natchitoches, LA |
| 20 | Sat Jan 25 | at Lamar | W70-62 | 17-3 | .850 | - | | Montagne Center · Beaumont, TX |
| 21 | Wed Jan 29 | vs Abilene Chrstn | W71-61 | 18-3 | .857 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 22 | Sat Feb 1 | at Sam Houston | W81-76 | 19-3 | .864 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 23 | Wed Feb 5 | vs Nicholls | W70-64 | 20-3 | .870 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 24 | Sat Feb 8 | vsNew Orleans | W81-74 | 21-3 | .875 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 25 | Wed Feb 12 | atTexas A&M-CC | W75-67 | 22-3 | .880 | - | | American Bank Center · Corpus Christi, TX |
| 26 | Wed Feb 19 | vsC Arkansas | W83-68 | 23-3 | .885 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 27 | Sat Feb 22 | atIncarnate Word | W80-56 | 24-3 | .889 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 28 | Wed Feb 26 | vsN'Western St | W90-59 | 25-3 | .893 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 29 | Sat Feb 29 | vsLamar | W95-76 | 26-3 | .897 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 30 | Tue Mar 3 | atAbilene Chrstn | W77-72 | 27-3 | .900 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 31 | Sat Mar 7 | vsSam Houston | W68-57 | 28-3 | .903 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
