| 1 | Sat Sep 12 | vs Louisiana | L14-31 | 0-1 | .000 | Jack Trice Stadium · Ames, IA |
| 2 | Sat Sep 26 | atTCU | W37-34 | 1-1 | .500 | Amon G. Carter Stadium · Fort Worth, TX |
| 3 | Sat Oct 3 | vs#18Oklahoma | W37-30 | 2-1 | .667 | Jack Trice Stadium · Ames, IA |
| 4 | Sat Oct 10 | vsTexas Tech | W31-15 | 3-1 | .750 | Jack Trice Stadium · Ames, IA |
| 5 | Sat Oct 24 | at#6Oklahoma St | L21-24 | 3-2 | .600 | Boone Pickens Stadium · Stillwater, OK |
| 6 | Sat Oct 31 | atKansas | W52-22 | 4-2 | .667 | David Booth Kansas Memorial Stadium · Lawrence, KS |
| 7 | Sat Nov 7 | vsBaylor | W38-31 | 5-2 | .714 | Jack Trice Stadium · Ames, IA |
| 8 | Sat Nov 21 | vsKansas St | W45-0 | 6-2 | .750 | Jack Trice Stadium · Ames, IA |
| 9 | Fri Nov 27 | at#17Texas | W23-20 | 7-2 | .778 | DKR-Texas Memorial Stadium · Austin, TX |
| 10 | Sat Dec 5 | vsWest Virginia | W42-6 | 8-2 | .800 | Jack Trice Stadium · Ames, IA |
| 11 | Sat Dec 19 | vs#10Oklahoma | L21-27 | 8-3 | .727 | Jack Trice Stadium · Ames, IA |
| BOWLS | Sat Jan 2 | vs#25Oregon | W34-17 | 9-3 | .750 | Jack Trice Stadium · Ames, IA |
