| 1 | Sat Aug 23 | at #17Kansas St | W24-21 | 1-0 | 1.000 | Bill Snyder Family Stadium · Manhattan, KS |
| 2 | Sat Aug 30 | vsSouth Dakota | W55-7 | 2-0 | 1.000 | Jack Trice Stadium · Ames, IA |
| 3 | Sat Sep 6 | vsIowa | W16-13 | 3-0 | 1.000 | Jack Trice Stadium · Ames, IA |
| 4 | Sat Sep 13 | atArkansas St | W24-16 | 4-0 | 1.000 | Centennial Bank Stadium · Jonesboro, AR |
| 5 | Sat Sep 27 | vsArizona | W39-14 | 5-0 | 1.000 | Jack Trice Stadium · Ames, IA |
| 6 | Sat Oct 4 | atCincinnati | L30-38 | 5-1 | .833 | Nippert Stadium · Cincinnati, OH |
| 7 | Sat Oct 11 | atColorado | L17-24 | 5-2 | .714 | Folsom Field · Boulder, CO |
| 8 | Sat Oct 25 | vs#11BYU | L27-41 | 5-3 | .625 | Jack Trice Stadium · Ames, IA |
| 9 | Sat Nov 1 | vsArizona St | L19-24 | 5-4 | .556 | Jack Trice Stadium · Ames, IA |
