| 1 | Sat Sep 3 | at Wyoming | L37-40 (2OT) | 0-1 | .000 | Jonah Field at War Memorial Stadium · Laramie, WY |
| 2 | Sat Sep 10 | vsN Illinois | W38-35 | 1-1 | .500 | Chapman Stadium · Tulsa, OK |
| 3 | Sat Sep 17 | vsJ'Ville St | W54-17 | 2-1 | .667 | Chapman Stadium · Tulsa, OK |
| 4 | Sat Sep 24 | at#16Ole Miss | L27-35 | 2-2 | .500 | Vaught-Hemingway Stadium · Oxford, MS |
| 5 | Sat Oct 1 | vsCincinnati | L21-31 | 2-3 | .400 | Chapman Stadium · Tulsa, OK |
| 6 | Sat Oct 8 | atNavy | L21-53 | 2-4 | .333 | Navy-Marine Corps Memorial Stadium · Annapolis, MD |
| 7 | Fri Oct 21 | atTemple | W27-16 | 3-4 | .429 | Lincoln Financial Field · Philadelphia, PA |
| 8 | Sat Oct 29 | vsSMU | L34-45 | 3-5 | .375 | Chapman Stadium · Tulsa, OK |
| 9 | Sat Nov 5 | vs#19Tulane | L13-27 | 3-6 | .333 | Chapman Stadium · Tulsa, OK |
| 10 | Thu Nov 10 | atMemphis | L10-26 | 3-7 | .300 | Simmons Bank Liberty Stadium · Memphis, TN |
| 11 | Fri Nov 18 | vsSouth Florida | W48-42 | 4-7 | .364 | Chapman Stadium · Tulsa, OK |
| 12 | Sat Nov 26 | atHouston | W37-30 | 5-7 | .417 | Robertson Stadium · Houston, TX |
