| 1 | Sat Sep 4 | vs ETSU | L3-23 | 0-1 | .000 | FirstBank Stadium · Nashville, TN |
| 2 | Sat Sep 11 | atColorado St | W24-21 | 1-1 | .500 | Hughes Stadium (CO) · Fort Collins, CO |
| 3 | Sat Sep 18 | vsStanford | L23-41 | 1-2 | .333 | FirstBank Stadium · Nashville, TN |
| 4 | Sat Sep 25 | vs#2Georgia | L0-62 | 1-3 | .250 | FirstBank Stadium · Nashville, TN |
| 5 | Sat Oct 2 | vsUConn | W30-28 | 2-3 | .400 | FirstBank Stadium · Nashville, TN |
| 6 | Sat Oct 9 | at#20Florida | L0-42 | 2-4 | .333 | Ben Hill Griffin Stadium · Gainesville, FL |
| 7 | Sat Oct 16 | atSouth Carolina | L20-21 | 2-5 | .286 | Williams-Brice Stadium · Columbia, SC |
| 8 | Sat Oct 23 | vsMississippi St | L6-45 | 2-6 | .250 | FirstBank Stadium · Nashville, TN |
| 9 | Sat Oct 30 | vsMissouri | L28-37 | 2-7 | .222 | FirstBank Stadium · Nashville, TN |
| 10 | Sat Nov 13 | vsKentucky | L17-34 | 2-8 | .200 | FirstBank Stadium · Nashville, TN |
| 11 | Sat Nov 20 | at#12Ole Miss | L17-31 | 2-9 | .182 | Vaught-Hemingway Stadium · Oxford, MS |
| 12 | Sat Nov 27 | atTennessee | L21-45 | 2-10 | .167 | Neyland Stadium · Knoxville, TN |
