| 1 | Wed Nov 25 | at ETSU | W70-47 | 1-0 | 1.000 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 2 | Fri Nov 27 | vs Austin Peay | W80-72 | 2-0 | 1.000 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 3 | Sat Nov 28 | at Omaha | W70-58 | 3-0 | 1.000 | - | | Baxter Arena · Omaha, NE |
| 4 | Tue Dec 1 | vs TBD | W81-51 | 4-0 | 1.000 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 5 | Sat Dec 5 | vs Tarleton | W69-48 | 5-0 | 1.000 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 6 | Wed Dec 9 | at #17Texas Tech | L44-51 | 5-1 | .833 | - | | United Supermarkets Arena · Lubbock, TX |
| 7 | Sat Dec 12 | vsTBD | W83-46 | 6-1 | .857 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 8 | Wed Dec 16 | vsTBD | W95-73 | 7-1 | .875 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 9 | Tue Dec 22 | at Arkansas | L72-85 | 7-2 | .778 | - | SEC Network | Bud Walton Arena · Fayetteville, AR |
| 10 | Tue Dec 29 | vsTBD | W82-44 | 8-2 | .800 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 11 | Sat Jan 2 | vs Lamar | W83-65 | 9-2 | .818 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 12 | Wed Jan 6 | at Hou Christian | W66-63 | 10-2 | .833 | - | | Sharp Gymnasium · Houston, TX |
| 13 | Sat Jan 16 | vs SE Louisiana | W76-42 | 11-2 | .846 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 14 | Wed Jan 20 | at Sam Houston | L57-64 | 11-3 | .786 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 15 | Sat Jan 23 | vs C Arkansas | W93-58 | 12-3 | .800 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 16 | Wed Jan 27 | vs SF Austin | W82-62 | 13-3 | .813 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 17 | Sat Jan 30 | at Incarnate Word | W75-67 | 14-3 | .824 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 18 | Mon Feb 1 | at Texas A&M-CC | PPD | 24-5 | .828 | - | | American Bank Center · Corpus Christi, TX |
| 19 | Sat Feb 6 | atLamar | W77-62 | 15-3 | .833 | - | | Montagne Center · Beaumont, TX |
| 20 | Mon Feb 8 | atTexas A&M-CC | W82-69 | 16-3 | .842 | - | | American Bank Center · Corpus Christi, TX |
| 21 | Wed Feb 10 | vsHou Christian | W88-59 | 17-3 | .850 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 22 | Sat Feb 13 | vsTexas A&M-CC | W83-55 | 18-3 | .857 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 24 | Wed Feb 24 | vsSam Houston | W86-72 | 19-3 | .864 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 25 | Sat Feb 27 | atC Arkansas | L82-84 | 19-4 | .826 | - | | Farris Center · Conway, AR |
| 26 | Wed Mar 3 | atSF Austin | W63-61 | 20-4 | .833 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 27 | Sat Mar 6 | vsIncarnate Word | W85-60 | 21-4 | .840 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 28 | Fri Mar 12 | vsLamar | W93-71 | 22-4 | .846 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 29 | Sat Mar 13 | at Nicholls | W79-45 | 23-4 | .852 | - | ESPN2 | David R. Stopher Gymnasium · Thibodaux, LA |
| 30 | Sat Mar 20 | at #3Texas | W53-52 | 24-4 | .857 | #14 | truTV | Moody Center · Austin, TX |
| 31 | Mon Mar 22 | at #11UCLA | L47-67 | 24-5 | .828 | #14 | TBS | Pauley Pavilion · Los Angeles, CA |
