| 1 | Tue Nov 5 | vs TBD | W90-39 | 1-0 | 1.000 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 2 | Sun Nov 10 | at Drexel | L83-86 (OT) | 1-1 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 3 | Sat Nov 16 | vs Pepperdine | L69-73 | 1-2 | .333 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 4 | Mon Nov 18 | at UNLV | L58-72 | 1-3 | .250 | - | | Thomas & Mack Center · Las Vegas, NV |
| 5 | Thu Nov 21 | vsTBD | W90-58 | 2-3 | .400 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 6 | Mon Nov 25 | at Texas St | L56-61 | 2-4 | .333 | - | | Strahan Arena at the University Events Center · San Marcos, TX |
| 7 | Fri Nov 29 | at SMU | L51-70 | 2-5 | .286 | - | | Moody Coliseum · Dallas, TX |
| 8 | Thu Dec 5 | vs SE Missouri St | W73-64 | 3-5 | .375 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 9 | Sat Dec 7 | vsTBD | W102-34 | 4-5 | .444 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 10 | Thu Dec 12 | vsTBD | W105-36 | 5-5 | .500 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 11 | Wed Dec 18 | at New Orleans | W77-71 | 6-5 | .545 | - | | Lakefront Arena · New Orleans, LA |
| 12 | Sat Dec 21 | vs Nicholls | W79-61 | 7-5 | .583 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 13 | Sun Dec 29 | at Wichita St | L66-84 | 7-6 | .538 | - | | Charles Koch Arena · Wichita, KS |
| 14 | Sat Jan 4 | at Lamar | W74-62 | 8-6 | .571 | - | | Montagne Center · Beaumont, TX |
| 15 | Wed Jan 8 | vs McNeese | L84-88 | 8-7 | .533 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 16 | Sat Jan 11 | vs Texas A&M-CC | W68-56 | 9-7 | .563 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 17 | Sat Jan 18 | vs SE Louisiana | W76-55 | 10-7 | .588 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 18 | Wed Jan 22 | at Sam Houston | L76-82 (OT) | 10-8 | .556 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 19 | Sat Jan 25 | at C Arkansas | W70-69 (OT) | 11-8 | .579 | - | | Farris Center · Conway, AR |
| 20 | Wed Jan 29 | at SF Austin | L61-71 | 11-9 | .550 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 21 | Sat Feb 1 | vs Incarnate Word | W72-58 | 12-9 | .571 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 22 | Wed Feb 5 | at N'Western St | L69-73 | 12-10 | .545 | - | | Prather Coliseum · Natchitoches, LA |
| 23 | Sat Feb 8 | vsLamar | W84-49 | 13-10 | .565 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 24 | Wed Feb 12 | vs Hou Christian | W81-67 | 14-10 | .583 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 25 | Sat Feb 15 | atTexas A&M-CC | W78-64 | 15-10 | .600 | - | | American Bank Center · Corpus Christi, TX |
| 26 | Wed Feb 19 | atHou Christian | W82-68 | 16-10 | .615 | - | | Sharp Gymnasium · Houston, TX |
| 27 | Sat Feb 22 | atSE Louisiana | W75-69 | 17-10 | .630 | - | | University Center (LA) · Hammond, LA |
| 28 | Wed Feb 26 | vsSam Houston | W85-69 | 18-10 | .643 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 29 | Sat Feb 29 | vsC Arkansas | W75-70 | 19-10 | .655 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 30 | Tue Mar 3 | vsSF Austin | L72-77 | 19-11 | .633 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 31 | Sat Mar 7 | atIncarnate Word | W71-68 (OT) | 20-11 | .645 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
