| 1 | Mon Nov 3 | vs TBD | W119-60 | 1-0 | 1.000 | - | ESPN+ | The Field House · Commerce, TX |
| 2 | Wed Nov 5 | atNew Mexico | L54-76 | 1-1 | .500 | - | | The Pit · Albuquerque, NM |
| 3 | Mon Nov 10 | atHawai'i | L74-100 | 1-2 | .333 | - | ESPN+ | Stan Sheriff Center · Honolulu, HI |
| 4 | Fri Nov 14 | atRice | L64-71 | 1-3 | .250 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 5 | Wed Nov 19 | vsTBD | W115-44 | 2-3 | .400 | - | ESPN+ | The Field House · Commerce, TX |
| 6 | Mon Nov 24 | atFairleigh | W70-65 | 3-3 | .500 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 7 | Tue Nov 25 | atArmy | W84-67 | 4-3 | .571 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 8 | Fri Dec 5 | at5UConn | L59-83 | 4-4 | .500 | - | Peacock | Gampel Pavilion · Storrs, CT |
| 9 | Sun Dec 7 | vsC Arkansas | W75-68 | 5-4 | .556 | - | ESPN+ | The Field House · Commerce, TX |
| 10 | Fri Dec 12 | atMcNeese | L66-102 | 5-5 | .500 | - | ESPN+ | Legacy Center · Lake Charles, LA |
| 11 | Mon Dec 15 | atSE Louisiana | W70-69 | 6-5 | .545 | - | ESPN+ | University Center (LA) · Hammond, LA |
| 12 | Sun Dec 21 | atTexas A&M | L77-118 | 6-6 | .500 | - | SECN+ | Reed Arena · College Station, TX |
| 13 | Mon Dec 29 | vsSF Austin | L48-75 | 6-7 | .462 | - | ESPN+ | The Field House · Commerce, TX |
| 14 | Wed Dec 31 | vsLamar | L62-69 | 6-8 | .429 | - | ESPN+ | The Field House · Commerce, TX |
| 15 | Sat Jan 3 | atNicholls | L58-80 | 6-9 | .400 | - | ESPN+ | David R. Stopher Gymnasium · Thibodaux, LA |
| 16 | Mon Jan 5 | atNew Orleans | L73-83 | 6-10 | .375 | - | ESPN+ | Lakefront Arena · New Orleans, LA |
| 17 | Sat Jan 10 | vsUT Rio Grande | W77-69 | 7-10 | .412 | - | ESPN+ | The Field House · Commerce, TX |
| 18 | Mon Jan 12 | vsTexas A&M-CC | L50-61 | 7-11 | .389 | - | ESPN+ | The Field House · Commerce, TX |
| 19 | Sat Jan 17 | atHou Christian | L70-81 | 7-12 | .368 | - | ESPN+ | Sharp Gymnasium · Houston, TX |
| 20 | Mon Jan 19 | atIncarnate Word | W80-58 | 8-12 | .400 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 21 | Sat Jan 24 | atN'Western St | PPD | 11-20 | .355 | - | | Prather Coliseum · Natchitoches, LA |
| 22 | Mon Jan 26 | atLamar | PPD | 11-20 | .355 | - | | Montagne Center · Beaumont, TX |
| 23 | Tue Jan 27 | atLamar | L61-82 | 8-13 | .381 | - | ESPN+ | Montagne Center · Beaumont, TX |
| 24 | Sat Jan 31 | vsNicholls | L68-72 | 8-14 | .364 | - | ESPN+ | The Field House · Commerce, TX |
| 25 | Mon Feb 2 | vsNew Orleans | L85-94 | 8-15 | .348 | - | ESPN+ | The Field House · Commerce, TX |
| 26 | Wed Feb 4 | atN'Western St | W74-68 | 9-15 | .375 | - | ESPN+ | Prather Coliseum · Natchitoches, LA |
| 27 | Sat Feb 7 | vsN'Western St | W52-48 | 10-15 | .400 | - | ESPN+ | The Field House · Commerce, TX |
| 28 | Mon Feb 9 | atSF Austin | L70-74 | 10-16 | .385 | - | ESPN+ | William R. Johnson Coliseum · Nacogdoches, TX |
| 29 | Sat Feb 14 | vsMcNeese | L54-97 | 10-17 | .370 | - | ESPN+ | The Field House · Commerce, TX |
| 30 | Mon Feb 16 | vsSE Louisiana | W70-53 | 11-17 | .393 | - | ESPN+ | The Field House · Commerce, TX |
| 31 | Sat Feb 21 | vsIncarnate Word | L73-82 | 11-18 | .379 | - | ESPN+ | The Field House · Commerce, TX |
| 32 | Mon Feb 23 | vsHou Christian | L68-69 | 11-19 | .367 | - | ESPN+ | The Field House · Commerce, TX |
| 33 | Sat Feb 28 | atUT Rio Grande | L55-63 | 11-20 | .355 | - | ESPN+ | UTRGV Fieldhouse · Edinburg, TX |
