| 1 | Wed Nov 6 | at Missouri | L42-82 | 0-1 | .000 | - | | Mizzou Arena · Columbia, MO |
| 2 | Fri Nov 8 | at N Colorado | L61-83 | 0-2 | .000 | - | | Bank of Colorado Arena · Greeley, CO |
| 3 | Tue Nov 12 | vs TBD | W86-60 | 1-2 | .333 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 4 | Sat Nov 16 | vs SIUE | L55-57 | 1-3 | .250 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 5 | Fri Nov 22 | vs Bethune | L58-83 | 1-4 | .200 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 6 | Sat Nov 23 | vsTBD | W68-44 | 2-4 | .333 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 7 | Sun Nov 24 | vs E Illinois | L63-72 | 2-5 | .286 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 8 | Sun Dec 1 | at Portland | L56-65 | 2-6 | .250 | - | | Chiles Center · Portland, OR |
| 9 | Tue Dec 3 | at Seattle U | L60-81 | 2-7 | .222 | - | | Redhawk Center · Seattle, WA |
| 10 | Sat Dec 7 | vsTBD | W101-65 | 3-7 | .300 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 11 | Wed Dec 18 | at C Arkansas | L82-88 (OT) | 3-8 | .273 | - | | Farris Center · Conway, AR |
| 12 | Sat Dec 21 | at Washington St | L59-87 | 3-9 | .250 | - | | Friel Court at Beasley Coliseum · Pullman, WA |
| 13 | Thu Jan 2 | at Nicholls | L60-76 | 3-10 | .231 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 14 | Wed Jan 8 | vs N'Western St | L66-72 | 3-11 | .214 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 15 | Sat Jan 11 | vs New Orleans | W73-70 | 4-11 | .267 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 16 | Wed Jan 15 | at McNeese | L56-72 | 4-12 | .250 | - | | Legacy Center · Lake Charles, LA |
| 17 | Sat Jan 18 | at SF Austin | L56-80 | 4-13 | .235 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 18 | Wed Jan 22 | vs Lamar | L77-89 | 4-14 | .222 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 19 | Sat Jan 25 | vs Texas A&M-CC | L47-68 | 4-15 | .211 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 20 | Wed Jan 29 | at Hou Christian | W84-82 | 5-15 | .250 | - | | Sharp Gymnasium · Houston, TX |
| 21 | Sat Feb 1 | at Abilene Chrstn | L58-72 | 5-16 | .238 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 22 | Wed Feb 5 | vs Sam Houston | W72-71 (OT) | 6-16 | .273 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 23 | Sat Feb 8 | vs SE Louisiana | W82-75 (OT) | 7-16 | .304 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 24 | Wed Feb 12 | atN'Western St | L60-70 | 7-17 | .292 | - | | Prather Coliseum · Natchitoches, LA |
| 25 | Sat Feb 15 | atNew Orleans | W67-66 | 8-17 | .320 | - | | Lakefront Arena · New Orleans, LA |
| 26 | Wed Feb 19 | vsMcNeese | W65-59 | 9-17 | .346 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 27 | Sat Feb 22 | vsSF Austin | L56-80 | 9-18 | .333 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 28 | Wed Feb 26 | atLamar | L66-86 | 9-19 | .321 | - | | Montagne Center · Beaumont, TX |
| 29 | Sat Feb 29 | atTexas A&M-CC | L70-78 | 9-20 | .310 | - | | American Bank Center · Corpus Christi, TX |
| 30 | Wed Mar 4 | vsHou Christian | L76-88 | 9-21 | .300 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 31 | Sat Mar 7 | vsAbilene Chrstn | L68-71 (OT) | 9-22 | .290 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
