| 1 | Tue Nov 9 | vs Texas St | L57-75 | 0-1 | .000 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 2 | Fri Nov 12 | at #8Baylor | L60-87 | 0-2 | .000 | - | | Ferrell Center · Waco, TX |
| 3 | Tue Nov 16 | vs TBD | L78-82 | 0-3 | .000 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 4 | Sat Nov 20 | vs Texas Tech | L62-84 | 0-4 | .000 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 5 | Fri Nov 26 | vs SE Missouri St | L76-79 | 0-5 | .000 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 6 | Sat Nov 27 | vs Montana St | L64-83 | 0-6 | .000 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 7 | Sun Nov 28 | vs Portland | L68-77 | 0-7 | .000 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 8 | Wed Dec 1 | vsTBD | W93-66 | 1-7 | .125 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 9 | Sat Dec 4 | at Abilene Chrstn | L65-98 | 1-8 | .111 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 10 | Sat Dec 11 | vs Grambling | W72-62 | 2-8 | .200 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 11 | Thu Dec 16 | at Rice | L55-85 | 2-9 | .182 | - | | Tudor Fieldhouse · Houston, TX |
| 12 | Mon Dec 20 | at #3Purdue | L59-79 | 2-10 | .167 | - | BTN | Mackey Arena · West Lafayette, IN |
| 13 | Tue Dec 28 | at #17Texas | L33-78 | 2-11 | .154 | - | LHN | Moody Center · Austin, TX |
| 15 | Sun Jan 2 | vsTBD | W90-45 | 3-11 | .214 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 16 | Thu Jan 6 | vs Nicholls | L56-87 | 3-12 | .200 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 17 | Fri Jan 7 | vs N'Western St | L80-83 | 3-13 | .188 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 18 | Sat Jan 8 | vs Hou Christian | W60-50 | 4-13 | .235 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 19 | Sat Jan 15 | at Texas A&M-CC | L64-80 | 4-14 | .222 | - | | American Bank Center · Corpus Christi, TX |
| 20 | Thu Jan 20 | vsHou Christian | L65-68 | 4-15 | .211 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 21 | Sat Jan 22 | vs McNeese | L72-82 | 4-16 | .200 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 22 | Thu Jan 27 | atN'Western St | L70-79 | 4-17 | .190 | - | | Prather Coliseum · Natchitoches, LA |
| 23 | Sat Jan 29 | at SE Louisiana | L68-78 | 4-18 | .182 | - | | University Center (LA) · Hammond, LA |
| 24 | Thu Feb 3 | vsNicholls | L60-63 | 4-19 | .174 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 25 | Sat Feb 5 | vs New Orleans | W78-70 | 5-19 | .208 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 26 | Thu Feb 10 | atNicholls | L58-69 | 5-20 | .200 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 27 | Sat Feb 12 | atNew Orleans | L57-84 | 5-21 | .192 | - | | Lakefront Arena · New Orleans, LA |
| 28 | Thu Feb 17 | vsN'Western St | L64-88 | 5-22 | .185 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 29 | Sat Feb 19 | vsSE Louisiana | W92-84 | 6-22 | .214 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 30 | Thu Feb 24 | atHou Christian | L68-82 | 6-23 | .207 | - | | Sharp Gymnasium · Houston, TX |
| 31 | Sat Feb 26 | atMcNeese | W69-67 | 7-23 | .233 | - | | Legacy Center · Lake Charles, LA |
| 32 | Sat Mar 5 | vsTexas A&M-CC | L68-77 | 7-24 | .226 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 33 | Wed Mar 9 | atHou Christian | L64-74 | 7-25 | .219 | - | | Sharp Gymnasium · Houston, TX |
