| 1 | Wed Nov 5 | vs TBD | W100-51 | - | 1-0 | 1.000 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 2 | Sat Nov 8 | vsTBD | W109-56 | - | 2-0 | 1.000 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 3 | Wed Nov 12 | atEvansville | W77-72 | - | 3-0 | 1.000 | - | ESPN+ | Ford Center · Evansville, IN |
| 4 | Wed Nov 19 | at7Michigan | L61-86 | - | 3-1 | .750 | - | Big Ten Network | Crisler Center · Ann Arbor, MI |
| 5 | Sun Nov 23 | vsMurray St | W90-87 | - | 4-1 | .800 | - | | Murphy Center · Murfreesboro, TN |
| 6 | Mon Nov 24 | vsG Washington | L79-92 | +9½ | 4-2 | .667 | - | | Murphy Center · Murfreesboro, TN |
| 7 | Tue Nov 25 | atMcNeese | L62-72 | +9½ | 4-3 | .571 | - | | Legacy Center · Lake Charles, LA |
| 8 | Mon Dec 1 | vsUAB | W76-61 | +1½ | 5-3 | .625 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 9 | Sun Dec 7 | vsBelmont | L62-83 | +3½ | 5-4 | .556 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 10 | Wed Dec 17 | vsKennesaw St | W68-67 | -3½ | 6-4 | .600 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 11 | Sun Dec 21 | vsTBD | W74-58 | - | 7-4 | .636 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 12 | Mon Dec 29 | at8Houston | L60-69 | +25½ | 7-5 | .583 | - | ESPN+ | Fertitta Center · Houston, TX |
| 13 | Fri Jan 2 | vsLouisiana Tech | W88-51 | -6½ | 8-5 | .615 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 14 | Sun Jan 4 | vsSam Houston | W68-67 | -4½ | 9-5 | .643 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 15 | Thu Jan 8 | atUTEP | L80-83 (OT) | -3½ | 9-6 | .600 | - | CBS Sports Network | Don Haskins Center · El Paso, TX |
| 16 | Sat Jan 10 | atNew Mexico St | W59-55 | +3½ | 10-6 | .625 | - | ESPNU | Pan American Center · Las Cruces, NM |
| 17 | Wed Jan 14 | atLouisiana Tech | L58-59 | -3½ | 10-7 | .588 | - | ESPN+ | Thomas Assembly Center · Ruston, LA |
| 18 | Sat Jan 17 | vsMissouri St | W90-87 (2OT) | -5½ | 11-7 | .611 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 19 | Fri Jan 23 | atJ'Ville St | L58-75 | -1½ | 11-8 | .579 | - | ESPN+ | Pete Mathews Coliseum · Jacksonville, AL |
| 20 | Thu Jan 29 | vsLiberty | L65-81 | +1½ | 11-9 | .550 | - | CBS Sports Network | Murphy Center · Murfreesboro, TN |
| 21 | Sat Jan 31 | vsWestern KY | L60-65 | -6½ | 11-10 | .524 | - | CBS Sports Network | Murphy Center · Murfreesboro, TN |
| 22 | Wed Feb 4 | vsFIU | L84-88 (OT) | -5½ | 11-11 | .500 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 23 | Sat Feb 7 | atDelaware | L88-89 (OT) | -5½ | 11-12 | .478 | - | ESPN+ | Bob Carpenter Center · Newark, DE |
| 24 | Thu Feb 12 | atKennesaw St | W90-87 | +3½ | 12-12 | .500 | - | CBS Sports Network | KSU Convocation Center · Kennesaw, GA |
| 25 | Sat Feb 14 | atWestern KY | L80-82 | +3½ | 12-13 | .480 | - | ESPN+ | E. A. Diddle Arena · Bowling Green, KY |
| 26 | Wed Feb 18 | atSam Houston | L70-78 | +3½ | 12-14 | .462 | - | ESPN+ | Bernard G. Johnson Coliseum · Huntsville, TX |
| 27 | Sat Feb 21 | vsDelaware | W78-66 | -10½ | 13-14 | .481 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 28 | Thu Feb 26 | vsUTEP | W77-67 | -8½ | 14-14 | .500 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 29 | Sat Feb 28 | vsNew Mexico St | W86-85 (OT) | -5½ | 15-14 | .517 | - | ESPN+ | Murphy Center · Murfreesboro, TN |
| 30 | Thu Mar 5 | atFIU | W73-67 | +1½ | 16-14 | .533 | - | ESPN+ | Ocean Bank Convocation Center · Miami, FL |
| 31 | Sat Mar 7 | atMissouri St | W75-63 | +2½ | 17-14 | .548 | - | ESPN+ | Great Southern Bank Arena · Springfield, MO |
| 32 | Thu Mar 12 | atLouisiana Tech | L69-80 | -1½ | 17-15 | .531 | - | ESPN+ | Thomas Assembly Center · Ruston, LA |
