| 1 | Mon Nov 6 | at #16Kentucky | L46-86 | 0-1 | .000 | - | SEC Network | Rupp Arena · Lexington, KY |
| 2 | Wed Nov 8 | vs TBD | W84-49 | 1-1 | .500 | - | | Pan American Center · Las Cruces, NM |
| 3 | Sat Nov 11 | at UC Irvine | L74-91 | 1-2 | .333 | - | | Bren Events Center · Irvine, CA |
| 4 | Tue Nov 14 | vsTBD | W78-43 | 2-2 | .500 | - | | Pan American Center · Las Cruces, NM |
| 5 | Sat Nov 18 | vs N Colorado | W76-71 | 3-2 | .600 | - | | Pan American Center · Las Cruces, NM |
| 6 | Tue Nov 21 | vs Fresno St | L76-81 (OT) | 3-3 | .500 | - | CBS | Pan American Center · Las Cruces, NM |
| 7 | Wed Nov 22 | vs S Illinois | L54-81 | 3-4 | .429 | - | | Pan American Center · Las Cruces, NM |
| 8 | Sun Nov 26 | at Louisville | L84-90 (OT) | 3-5 | .375 | - | | KFC Yum! Center · Louisville, KY |
| 9 | Tue Nov 28 | vsTBD | W84-49 | 4-5 | .444 | - | | Pan American Center · Las Cruces, NM |
| 10 | Sat Dec 2 | at New Mexico | L62-106 | 4-6 | .400 | - | | The Pit · Albuquerque, NM |
| 11 | Tue Dec 12 | vsTBD | W76-71 | 5-6 | .455 | - | | Pan American Center · Las Cruces, NM |
| 12 | Fri Dec 15 | vsNew Mexico | L72-73 | 5-7 | .417 | - | CBS | Pan American Center · Las Cruces, NM |
| 13 | Tue Dec 19 | at SF Austin | L72-75 | 5-8 | .385 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 14 | Fri Dec 22 | at Tulsa | L59-65 | 5-9 | .357 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 15 | Sat Dec 30 | vs CA Baptist | W66-61 | 6-9 | .400 | - | | Pan American Center · Las Cruces, NM |
| 16 | Thu Jan 4 | vs UTEP | W63-53 | 7-9 | .438 | - | CBS | Pan American Center · Las Cruces, NM |
| 17 | Thu Jan 11 | at FIU | L67-77 | 7-10 | .412 | - | | Ocean Bank Convocation Center · Miami, FL |
| 18 | Thu Jan 18 | vs Western KY | W72-70 | 8-10 | .444 | - | | Pan American Center · Las Cruces, NM |
| 19 | Sat Jan 20 | vs MTSU | W73-62 | 9-10 | .474 | - | | Pan American Center · Las Cruces, NM |
| 20 | Thu Jan 25 | at Sam Houston | L67-79 | 9-11 | .450 | - | CBS | Bernard G. Johnson Coliseum · Huntsville, TX |
| 21 | Sat Jan 27 | at Louisiana Tech | L53-73 | 9-12 | .429 | - | | Thomas Assembly Center · Ruston, LA |
| 22 | Thu Feb 1 | vs Liberty | W79-73 (OT) | 10-12 | .455 | - | | Pan American Center · Las Cruces, NM |
| 23 | Sat Feb 3 | vs J'Ville St | W67-65 | 11-12 | .478 | - | | Pan American Center · Las Cruces, NM |
| 24 | Sat Feb 10 | atUTEP | L49-74 | 11-13 | .458 | - | | Don Haskins Center · El Paso, TX |
| 25 | Thu Feb 15 | atMTSU | L69-76 | 11-14 | .440 | - | | Murphy Center · Murfreesboro, TN |
| 26 | Sat Feb 17 | atWestern KY | L58-72 | 11-15 | .423 | - | | E. A. Diddle Arena · Bowling Green, KY |
| 27 | Thu Feb 22 | vsSam Houston | L58-79 | 11-16 | .407 | - | CBS | Pan American Center · Las Cruces, NM |
| 28 | Sat Feb 24 | vsLouisiana Tech | L58-67 | 11-17 | .393 | - | | Pan American Center · Las Cruces, NM |
| 29 | Thu Feb 29 | atLiberty | L58-83 | 11-18 | .379 | - | CBS | Liberty Arena · Lynchburg, VA |
| 30 | Sat Mar 2 | atJ'Ville St | W66-64 | 12-18 | .400 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 31 | Sat Mar 9 | vsFIU | W77-70 | 13-18 | .419 | - | | Pan American Center · Las Cruces, NM |
| 32 | Thu Mar 14 | atWestern KY | L69-89 | 13-19 | .406 | - | | E. A. Diddle Arena · Bowling Green, KY |
