| 1 | Wed Nov 25 | at SMU | L67-97 | 0-1 | .000 | - | | Moody Coliseum · Dallas, TX |
| 2 | Fri Nov 27 | at14Texas Tech | L52-84 | 0-2 | .000 | - | ESPNU | United Supermarkets Arena · Lubbock, TX |
| 3 | Sun Nov 29 | vsBoise St | L55-86 | 0-3 | .000 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 4 | Fri Dec 4 | vsTBD | W117-42 | 1-3 | .250 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 5 | Sun Dec 6 | vsTBD | W117-54 | 2-3 | .400 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 7 | Thu Dec 10 | vsTBD | W107-65 | 3-3 | .500 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 8 | Mon Dec 14 | atLSU | L66-88 | 3-4 | .429 | - | SEC Network | Pete Maravich Assembly Center · Baton Rouge, LA |
| 9 | Wed Dec 16 | at11Texas | L63-79 | 3-5 | .375 | - | LHN | Moody Center · Austin, TX |
| 10 | Sat Dec 19 | vsRice | W82-69 | 4-5 | .444 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 11 | Mon Dec 21 | atUT Rio Grande | W69-66 | 5-5 | .500 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 12 | Tue Dec 29 | vsTBD | W101-59 | 6-5 | .545 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 13 | Sat Jan 2 | atNicholls | W84-81 | 7-5 | .583 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 14 | Wed Jan 6 | atSE Louisiana | W70-52 | 8-5 | .615 | - | | University Center (LA) · Hammond, LA |
| 15 | Sat Jan 9 | atC Arkansas | W91-80 | 9-5 | .643 | - | | Farris Center · Conway, AR |
| 16 | Wed Jan 13 | vsLamar | W96-71 | 10-5 | .667 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 17 | Sat Jan 16 | vsHou Christian | W87-80 | 11-5 | .688 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 18 | Wed Jan 20 | vsAbilene Chrstn | W64-57 | 12-5 | .706 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 19 | Wed Jan 27 | atTexas A&M-CC | W75-70 | 13-5 | .722 | - | | American Bank Center · Corpus Christi, TX |
| 20 | Sun Jan 31 | atSF Austin | L68-78 | 13-6 | .684 | - | ESPNU | William R. Johnson Coliseum · Nacogdoches, TX |
| 21 | Sat Feb 6 | vsNicholls | W78-71 | 14-6 | .700 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 22 | Wed Feb 10 | vsSE Louisiana | W79-61 | 15-6 | .714 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 23 | Sat Feb 13 | vsC Arkansas | W97-57 | 16-6 | .727 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 24 | Sat Feb 20 | atHou Christian | PPD | 19-9 | .679 | - | | Sharp Gymnasium · Houston, TX |
| 25 | Mon Feb 22 | atLamar | W77-71 | 17-6 | .739 | - | | Montagne Center · Beaumont, TX |
| 26 | Wed Feb 24 | atAbilene Chrstn | L72-86 | 17-7 | .708 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 27 | Mon Mar 1 | atHou Christian | W83-70 | 18-7 | .720 | - | | Sharp Gymnasium · Houston, TX |
| 28 | Wed Mar 3 | vsTexas A&M-CC | W84-61 | 19-7 | .731 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 29 | Sat Mar 6 | vsSF Austin | L59-64 | 19-8 | .704 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 30 | Thu Mar 11 | vsLamar | L69-70 | 19-9 | .679 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
