| 1 | Tue Nov 5 | vs TBD | W95-57 | 1-0 | 1.000 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 2 | Fri Nov 8 | atMississippi St | L58-67 | 1-1 | .500 | - | | Humphrey Coliseum · Starkville, MS |
| 3 | Sat Nov 16 | atC Michigan | L77-84 | 1-2 | .333 | - | | McGuirk Arena · Mount Pleasant, MI |
| 4 | Wed Nov 20 | vsTBD | W88-58 | 2-2 | .500 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 5 | Sat Nov 23 | atSan Francisco | L81-90 | 2-3 | .400 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 6 | Tue Nov 26 | atBakersfield | W74-65 | 3-3 | .500 | - | | Icardo Center · Bakersfield, CA |
| 7 | Sat Nov 30 | vsTBD | W86-51 | 4-3 | .571 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 8 | Tue Dec 3 | atUT Rio Grande | L86-90 (2OT) | 4-4 | .500 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 9 | Sun Dec 8 | vsLouisiana Tech | W71-68 | 5-4 | .556 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 10 | Sun Dec 15 | vsTBD | W91-58 | 6-4 | .600 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 11 | Wed Dec 18 | vsN'Western St | W92-79 | 7-4 | .636 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 12 | Sat Dec 21 | vsNew Orleans | W87-79 | 8-4 | .667 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 13 | Sun Dec 29 | atRice | W75-61 | 9-4 | .692 | - | | Tudor Fieldhouse · Houston, TX |
| 14 | Thu Jan 2 | atMcNeese | W94-75 | 10-4 | .714 | - | | Legacy Center · Lake Charles, LA |
| 15 | Sat Jan 4 | vsNicholls | L58-70 | 10-5 | .667 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 16 | Wed Jan 8 | vsSE Louisiana | W67-62 | 11-5 | .688 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 17 | Sat Jan 11 | atC Arkansas | L82-89 | 11-6 | .647 | - | | Farris Center · Conway, AR |
| 18 | Wed Jan 15 | atLamar | W80-75 (OT) | 12-6 | .667 | - | | Montagne Center · Beaumont, TX |
| 19 | Sat Jan 18 | atHou Christian | W95-75 | 13-6 | .684 | - | | Sharp Gymnasium · Houston, TX |
| 20 | Wed Jan 22 | vsAbilene Chrstn | W82-76 (OT) | 14-6 | .700 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 21 | Wed Jan 29 | vsTexas A&M-CC | W80-61 | 15-6 | .714 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 22 | Sat Feb 1 | vsSF Austin | L76-81 | 15-7 | .682 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 23 | Wed Feb 5 | atIncarnate Word | L71-72 (OT) | 15-8 | .652 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 24 | Sat Feb 8 | atNicholls | L82-88 | 15-9 | .625 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 25 | Wed Feb 12 | atSE Louisiana | W79-70 | 16-9 | .640 | - | | University Center (LA) · Hammond, LA |
| 26 | Sat Feb 15 | vsC Arkansas | W82-67 | 17-9 | .654 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 27 | Wed Feb 19 | vsLamar | L65-77 | 17-10 | .630 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 28 | Sat Feb 22 | vsHou Christian | W77-73 | 18-10 | .643 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 29 | Wed Feb 26 | atAbilene Chrstn | L69-85 | 18-11 | .621 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 30 | Wed Mar 4 | atTexas A&M-CC | L60-74 | 18-12 | .600 | - | | American Bank Center · Corpus Christi, TX |
| 31 | Sat Mar 7 | atSF Austin | L57-68 | 18-13 | .581 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
