| 1 | Fri Jul 24 | at Rangers | L0-1 | 0-1 | .000 | Globe Life Field · Arlington, TX |
| 2 | Sat Jul 25 | atRangers | W3-2 | 1-1 | .500 | Globe Life Field · Arlington, TX |
| 3 | Sun Jul 26 | atRangers | W5-2 | 2-1 | .667 | Globe Life Field · Arlington, TX |
| 4 | Tue Jul 28 | at Athletics | W8-3 | 3-1 | .750 | RingCentral Coliseum · Oakland, CA |
| 5 | Wed Jul 29 | atAthletics | W5-1 | 4-1 | .800 | RingCentral Coliseum · Oakland, CA |
| 6 | Fri Jul 31 | vs Padres | L7-8 | 4-2 | .667 | Coors Field · Denver, CO |
| 7 | Sat Aug 1 | vsPadres | W6-1 | 5-2 | .714 | Coors Field · Denver, CO |
| 8 | Sun Aug 2 | vsPadres | W9-6 | 6-2 | .750 | Coors Field · Denver, CO |
| 9 | Mon Aug 3 | vs Giants | W7-6 | 7-2 | .778 | Coors Field · Denver, CO |
| 10 | Tue Aug 4 | vsGiants | W5-2 | 8-2 | .800 | Coors Field · Denver, CO |
| 11 | Wed Aug 5 | vsGiants | L3-4 | 8-3 | .727 | Coors Field · Denver, CO |
| 12 | Thu Aug 6 | vsGiants | W6-4 | 9-3 | .750 | Coors Field · Denver, CO |
| 13 | Fri Aug 7 | at Mariners | W8-4 | 10-3 | .769 | T-Mobile Park · Seattle, WA |
| 14 | Sat Aug 8 | atMariners | W5-0 | 11-3 | .786 | T-Mobile Park · Seattle, WA |
| 15 | Sun Aug 9 | atMariners | L3-5 | 11-4 | .733 | T-Mobile Park · Seattle, WA |
| 16 | Mon Aug 10 | vs D-backs | L8-12 | 11-5 | .688 | Coors Field · Denver, CO |
| 17 | Tue Aug 11 | vsD-backs | W8-7 | 12-5 | .706 | Coors Field · Denver, CO |
| 18 | Wed Aug 12 | vsD-backs | L7-13 | 12-6 | .667 | Coors Field · Denver, CO |
| 19 | Fri Aug 14 | vsRangers | L2-3 | 12-7 | .632 | Coors Field · Denver, CO |
| 20 | Sat Aug 15 | vsRangers | L4-6 | 12-8 | .600 | Coors Field · Denver, CO |
| 21 | Sun Aug 16 | vsRangers | W10-6 | 13-8 | .619 | Coors Field · Denver, CO |
| 22 | Mon Aug 17 | at Astros | L1-2 | 13-9 | .591 | Minute Maid Park · Houston, TX |
| 23 | Tue Aug 18 | atAstros | L1-2 (11) | 13-10 | .565 | Minute Maid Park · Houston, TX |
| 24 | Wed Aug 19 | vsAstros | L6-13 | 13-11 | .542 | Coors Field · Denver, CO |
| 25 | Thu Aug 20 | vsAstros | L8-10 | 13-12 | .520 | Coors Field · Denver, CO |
| 26 | Fri Aug 21 | at Dodgers | L1-5 | 13-13 | .500 | Dodger Stadium · Los Angeles, CA |
| 27 | Sat Aug 22 | atDodgers | L3-4 | 13-14 | .481 | Dodger Stadium · Los Angeles, CA |
| 28 | Sun Aug 23 | atDodgers | L3-11 | 13-15 | .464 | Dodger Stadium · Los Angeles, CA |
| 29 | Mon Aug 24 | atD-backs | W3-2 | 14-15 | .483 | Chase Field · Phoenix, AZ |
| 30 | Tue Aug 25 | atD-backs | W5-4 | 15-15 | .500 | Chase Field · Phoenix, AZ |
| 31 | Wed Aug 26 | atD-backs | W8-7 | 16-15 | .516 | Chase Field · Phoenix, AZ |
| 32 | Fri Aug 28 | vsPadres | L4-10 | 16-16 | .500 | Coors Field · Denver, CO |
| 33 | Sat Aug 29 | vsPadres | W4-3 | 17-16 | .515 | Coors Field · Denver, CO |
| 34 | Sun Aug 30 | vsPadres | L2-13 | 17-17 | .500 | Coors Field · Denver, CO |
| 35 | Mon Aug 31 | vsPadres | L0-6 | 17-18 | .486 | Coors Field · Denver, CO |
| 36 | Tue Sep 1 | vsGiants | L5-23 | 17-19 | .472 | Coors Field · Denver, CO |
| 37 | Wed Sep 2 | vsGiants | W9-6 | 18-19 | .486 | Coors Field · Denver, CO |
| 38 | Fri Sep 4 | atDodgers | L6-10 | 18-20 | .474 | Dodger Stadium · Los Angeles, CA |
| 39 | Sat Sep 5 | atDodgers | W5-2 | 19-20 | .487 | Dodger Stadium · Los Angeles, CA |
| 40 | Sun Sep 6 | atDodgers | W7-6 | 20-20 | .500 | Dodger Stadium · Los Angeles, CA |
| 41 | Mon Sep 7 | atPadres | L0-1 | 20-21 | .488 | Petco Park · San Diego, CA |
| 42 | Tue Sep 8 | atPadres | L5-14 | 20-22 | .476 | Petco Park · San Diego, CA |
| 43 | Wed Sep 9 | atPadres | L3-5 | 20-23 | .465 | Petco Park · San Diego, CA |
| 44 | Fri Sep 11 | vs Angels | W8-4 | 21-23 | .477 | Coors Field · Denver, CO |
| 45 | Sat Sep 12 | vsAngels | L2-5 (11) | 21-24 | .467 | Coors Field · Denver, CO |
| 46 | Sun Sep 13 | vsAngels | L3-5 | 21-25 | .457 | Coors Field · Denver, CO |
| 47 | Tue Sep 15 | vsAthletics | W3-1 | 22-25 | .468 | Coors Field · Denver, CO |
| 48 | Wed Sep 16 | vsAthletics | L1-3 | 22-26 | .458 | Coors Field · Denver, CO |
| 49 | Thu Sep 17 | vsDodgers | L3-9 | 22-27 | .449 | Coors Field · Denver, CO |
| 50 | Fri Sep 18 | vsDodgers | L6-15 | 22-28 | .440 | Coors Field · Denver, CO |
| 51 | Sat Sep 19 | vsDodgers | L1-6 | 22-29 | .431 | Coors Field · Denver, CO |
| 52 | Sun Sep 20 | vsDodgers | W6-3 | 23-29 | .442 | Coors Field · Denver, CO |
| 53 | Mon Sep 21 | atGiants | W7-2 | 24-29 | .453 | Oracle Park · San Francisco, CA |
| 54 | Tue Sep 22 | atGiants | L2-5 | 24-30 | .444 | Oracle Park · San Francisco, CA |
| 55 | Wed Sep 23 | atGiants | L2-7 | 24-31 | .436 | Oracle Park · San Francisco, CA |
| 56 | Thu Sep 24 | atGiants | W5-4 (11) | 25-31 | .446 | Oracle Park · San Francisco, CA |
| 57 | Fri Sep 25 | atD-backs | L0-4 | 25-32 | .439 | Chase Field · Phoenix, AZ |
| 58 | Fri Sep 25 | atD-backs | L5-11 | 25-33 | .431 | Chase Field · Phoenix, AZ |
| 59 | Sat Sep 26 | atD-backs | W10-3 | 26-33 | .441 | Chase Field · Phoenix, AZ |
| 60 | Sun Sep 27 | atD-backs | L3-11 | 26-34 | .433 | Chase Field · Phoenix, AZ |
