| 1 | Sat Sep 3 | vs S Dakota St | W7-3 | 1-0 | 1.000 | Kinnick Stadium · Iowa City, IA |
| 2 | Sat Sep 10 | vsIowa State | L7-10 | 1-1 | .500 | Kinnick Stadium · Iowa City, IA |
| 3 | Sat Sep 17 | vsNevada | W27-0 | 2-1 | .667 | Kinnick Stadium · Iowa City, IA |
| 4 | Sat Sep 24 | atRutgers | W27-10 | 3-1 | .750 | HighPoint.com Stadium · Piscataway, NJ |
| 5 | Sat Oct 1 | vs#4Michigan | L14-27 | 3-2 | .600 | Kinnick Stadium · Iowa City, IA |
| 6 | Sat Oct 8 | atIllinois | L6-9 | 3-3 | .500 | Alumni Memorial Field at Foster Stadium · Lexington, VA |
| 7 | Sat Oct 22 | at#2Ohio State | L10-54 | 3-4 | .429 | Ohio Stadium · Columbus, OH |
| 8 | Sat Oct 29 | vsNorthwestern | W33-13 | 4-4 | .500 | Kinnick Stadium · Iowa City, IA |
| 9 | Sat Nov 5 | atPurdue | W24-3 | 5-4 | .556 | Ross-Ade Stadium · West Lafayette, IN |
| 10 | Sat Nov 12 | vsWisconsin | W24-10 | 6-4 | .600 | Kinnick Stadium · Iowa City, IA |
| 11 | Sat Nov 19 | atMinnesota | W13-10 | 7-4 | .636 | Huntington Bank Stadium · Minneapolis, MN |
| 12 | Fri Nov 25 | vsNebraska | L17-24 | 7-5 | .583 | Kinnick Stadium · Iowa City, IA |
| BOWLS | Sat Dec 31 | atKentucky | W21-0 | 8-5 | .615 | Kroger Field · Lexington, KY |
