| 1 | Sat Sep 2 | vs Ball State | W44-14 | 1-0 | 1.000 | Kroger Field · Lexington, KY |
| 2 | Sat Sep 9 | vsE Kentucky | W28-17 | 2-0 | 1.000 | Kroger Field · Lexington, KY |
| 3 | Sat Sep 16 | vsAkron | W35-3 | 3-0 | 1.000 | Kroger Field · Lexington, KY |
| 4 | Sat Sep 23 | atVanderbilt | W45-28 | 4-0 | 1.000 | FirstBank Stadium · Nashville, TN |
| 5 | Sat Sep 30 | vs#22Florida | W33-14 | 5-0 | 1.000 | Kroger Field · Lexington, KY |
| 6 | Sat Oct 7 | at#1Georgia | L13-51 | 5-1 | .833 | Sanford Stadium · Athens, GA |
| 7 | Sat Oct 14 | vsMissouri | L21-38 | 5-2 | .714 | Kroger Field · Lexington, KY |
| 8 | Sat Oct 28 | vs#21Tennessee | L27-33 | 5-3 | .625 | Kroger Field · Lexington, KY |
| 9 | Sat Nov 4 | atMississippi St | W24-3 | 6-3 | .667 | Davis Wade Stadium · Starkville, MS |
| 10 | Sat Nov 11 | vs#8Alabama | L21-49 | 6-4 | .600 | Kroger Field · Lexington, KY |
| 11 | Sat Nov 18 | atSouth Carolina | L14-17 | 6-5 | .545 | Williams-Brice Stadium · Columbia, SC |
| 12 | Sat Nov 25 | at#10Louisville | W38-31 | 7-5 | .583 | Cardinal Stadium · Louisville, KY |
| BOWLS | Fri Dec 29 | vs#22Clemson | L35-38 | 7-6 | .538 | Kroger Field · Lexington, KY |
