| 1 | Tue Nov 9 | at 5Texas | L48-92 | +37½ | 0-1 | .000 | - | | Moody Center · Austin, TX |
| 2 | Sat Nov 13 | vsTBD | W122-44 | - | 1-1 | .500 | - | | Sharp Gymnasium · Houston, TX |
| 3 | Wed Nov 17 | atTexas A&M | L39-73 | +23½ | 1-2 | .333 | - | | Reed Arena · College Station, TX |
| 4 | Sun Nov 21 | atDenver | L61-74 | +5½ | 1-3 | .250 | - | | Hamilton Gymnasium · Denver, CO |
| 5 | Wed Nov 24 | atOklahoma | L40-57 | +34½ | 1-4 | .200 | - | | Lloyd Noble Center · Norman, OK |
| 6 | Mon Nov 29 | vsTBD | W100-62 | - | 2-4 | .333 | - | | Sharp Gymnasium · Houston, TX |
| 7 | Sat Dec 4 | vsOral Roberts | L67-85 | +14½ | 2-5 | .286 | - | | Sharp Gymnasium · Houston, TX |
| 8 | Tue Dec 7 | vsTBD | W84-67 | - | 3-5 | .375 | - | | Sharp Gymnasium · Houston, TX |
| 9 | Sat Dec 11 | vsRice | L73-88 | +14½ | 3-6 | .333 | - | | Sharp Gymnasium · Houston, TX |
| 11 | Mon Jan 3 | vsTBD | W94-63 | - | 4-6 | .400 | - | | Sharp Gymnasium · Houston, TX |
| 12 | Thu Jan 6 | vsSE Louisiana | L81-90 | -7½ | 4-7 | .364 | - | | Sharp Gymnasium · Houston, TX |
| 13 | Fri Jan 7 | atNew Orleans | L65-81 | -9 | 4-8 | .333 | - | | Lakefront Arena · New Orleans, LA |
| 14 | Sat Jan 8 | atIncarnate Word | L50-60 | +2 | 4-9 | .308 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 15 | Sat Jan 15 | atMcNeese | L75-78 | +9 | 4-10 | .286 | - | | Legacy Center · Lake Charles, LA |
| 16 | Thu Jan 20 | atIncarnate Word | W68-65 | +2 | 5-10 | .333 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 17 | Sat Jan 22 | atTexas A&M-CC | W77-71 | +13 | 6-10 | .375 | - | | American Bank Center · Corpus Christi, TX |
| 18 | Thu Jan 27 | vsNew Orleans | L66-77 | +3½ | 6-11 | .353 | - | | Sharp Gymnasium · Houston, TX |
| 19 | Sat Jan 29 | vsNicholls | L61-73 | +9 | 6-12 | .333 | - | | Sharp Gymnasium · Houston, TX |
| 20 | Thu Feb 3 | vsN'Western St | L87-97 | +2 | 6-13 | .316 | - | | Sharp Gymnasium · Houston, TX |
| 21 | Sat Feb 5 | vsSE Louisiana | W93-80 | +5 | 7-13 | .350 | - | | Sharp Gymnasium · Houston, TX |
| 22 | Thu Feb 10 | atN'Western St | W76-69 | +5½ | 8-13 | .381 | - | | Prather Coliseum · Natchitoches, LA |
| 23 | Sat Feb 12 | atSE Louisiana | L84-89 | +7½ | 8-14 | .364 | - | | University Center (LA) · Hammond, LA |
| 24 | Sat Feb 19 | atNicholls | L70-84 | +12½ | 8-15 | .348 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 25 | Thu Feb 24 | vsIncarnate Word | W82-68 | -5½ | 9-15 | .375 | - | | Sharp Gymnasium · Houston, TX |
| 26 | Sat Feb 26 | vsTexas A&M-CC | L70-75 | +3 | 9-16 | .360 | - | | Sharp Gymnasium · Houston, TX |
| 27 | Wed Mar 2 | atNew Orleans | L74-75 | +8½ | 9-17 | .346 | - | | Lakefront Arena · New Orleans, LA |
| 28 | Sat Mar 5 | vsMcNeese | W149-144 (4OT) | -2 | 10-17 | .370 | - | | Sharp Gymnasium · Houston, TX |
| 29 | Wed Mar 9 | vsIncarnate Word | W74-64 | -4½ | 11-17 | .393 | - | | Sharp Gymnasium · Houston, TX |
| 30 | Thu Mar 10 | atTexas A&M-CC | L60-75 | +5½ | 11-18 | .379 | - | | American Bank Center · Corpus Christi, TX |
