| 1 | Tue Nov 5 | at Tulsa | L72-80 | 0-1 | .000 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 2 | Fri Nov 8 | atOral Roberts | L81-95 | 0-2 | .000 | - | | Mabee Center · Tulsa, OK |
| 3 | Wed Nov 13 | at11Texas Tech | L74-103 | 0-3 | .000 | - | | United Supermarkets Arena · Lubbock, TX |
| 4 | Fri Nov 22 | atMichigan | L68-111 | 0-4 | .000 | - | | Crisler Center · Ann Arbor, MI |
| 5 | Tue Nov 26 | atHouston | L73-112 | 0-5 | .000 | - | | Fertitta Center · Houston, TX |
| 6 | Tue Dec 3 | at19Dayton | L68-99 | 0-6 | .000 | - | | UD Arena · Dayton, OH |
| 7 | Sat Dec 7 | vsSamford | L90-113 | 0-7 | .000 | - | | Sharp Gymnasium · Houston, TX |
| 8 | Sat Dec 14 | atRice | L84-96 | 0-8 | .000 | - | | Tudor Fieldhouse · Houston, TX |
| 9 | Wed Dec 18 | atSF Austin | L68-96 | 0-9 | .000 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 10 | Sun Dec 22 | atNew Mexico | L88-107 | 0-10 | .000 | - | | The Pit · Albuquerque, NM |
| 11 | Thu Jan 2 | vsC Arkansas | W111-107 (OT) | 1-10 | .091 | - | | Sharp Gymnasium · Houston, TX |
| 12 | Sun Jan 5 | atN'Western St | L79-106 | 1-11 | .083 | - | | Prather Coliseum · Natchitoches, LA |
| 13 | Sat Jan 11 | vsLamar | L92-102 | 1-12 | .077 | - | | Sharp Gymnasium · Houston, TX |
| 14 | Wed Jan 15 | vsNew Orleans | L98-106 | 1-13 | .071 | - | | Sharp Gymnasium · Houston, TX |
| 15 | Sat Jan 18 | vsSam Houston | L75-95 | 1-14 | .067 | - | | Sharp Gymnasium · Houston, TX |
| 16 | Wed Jan 22 | atNicholls | L83-91 | 1-15 | .063 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 17 | Sat Jan 25 | atMcNeese | L89-102 | 1-16 | .059 | - | | Legacy Center · Lake Charles, LA |
| 18 | Wed Jan 29 | vsIncarnate Word | L82-84 | 1-17 | .056 | - | | Sharp Gymnasium · Houston, TX |
| 19 | Sat Feb 1 | vsTexas A&M-CC | W82-77 | 2-17 | .105 | - | | Sharp Gymnasium · Houston, TX |
| 20 | Wed Feb 5 | atSE Louisiana | W79-76 | 3-17 | .150 | - | | University Center (LA) · Hammond, LA |
| 21 | Sat Feb 8 | vsN'Western St | L79-93 | 3-18 | .143 | - | | Sharp Gymnasium · Houston, TX |
| 22 | Wed Feb 12 | atAbilene Chrstn | L67-81 | 3-19 | .136 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 23 | Sat Feb 15 | atLamar | L69-79 | 3-20 | .130 | - | | Montagne Center · Beaumont, TX |
| 24 | Wed Feb 19 | vsAbilene Chrstn | L68-82 | 3-21 | .125 | - | | Sharp Gymnasium · Houston, TX |
| 25 | Sat Feb 22 | atSam Houston | L73-77 | 3-22 | .120 | - | | Bernard G. Johnson Coliseum · Huntsville, TX |
| 26 | Wed Feb 26 | vsNicholls | L85-93 | 3-23 | .115 | - | | Sharp Gymnasium · Houston, TX |
| 27 | Sat Feb 29 | vsMcNeese | L80-100 | 3-24 | .111 | - | | Sharp Gymnasium · Houston, TX |
| 28 | Wed Mar 4 | atIncarnate Word | W88-76 | 4-24 | .143 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 29 | Sat Mar 7 | atTexas A&M-CC | L78-84 | 4-25 | .138 | - | | American Bank Center · Corpus Christi, TX |
