| 1 | Wed Nov 25 | at Pitt | W80-70 | 1-0 | 1.000 | - | | Petersen Events Center · Pittsburgh, PA |
| 2 | Sat Nov 28 | vs UMBC | L65-80 | 1-1 | .500 | - | | DeGol Arena · Loretto, PA |
| 3 | Tue Dec 1 | at #15Virginia | L51-76 | 1-2 | .333 | - | ACC Network | John Paul Jones Arena · Charlottesville, VA |
| 4 | Thu Dec 3 | at Liberty | L62-78 | 1-3 | .250 | - | | Liberty Arena · Lynchburg, VA |
| 5 | Tue Dec 8 | at Mount St Mary | L57-75 | 1-4 | .200 | - | | Knott Arena · Emmitsburg, MD |
| 7 | Thu Jan 7 | at Long Island | L75-78 | 1-5 | .167 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 8 | Fri Jan 8 | atLong Island | L58-71 | 1-6 | .143 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 9 | Thu Jan 14 | vs Bryant | W89-82 | 2-6 | .250 | - | | DeGol Arena · Loretto, PA |
| 10 | Fri Jan 15 | vsBryant | L63-72 | 2-7 | .222 | - | | DeGol Arena · Loretto, PA |
| 11 | Thu Jan 21 | at Sacred Heart | W76-58 | 3-7 | .300 | - | | William H. Pitt Center · Fairfield, CT |
| 12 | Fri Jan 22 | atSacred Heart | L70-82 | 3-8 | .273 | - | | William H. Pitt Center · Fairfield, CT |
| 13 | Tue Jan 26 | vs Fairleigh | L92-94 (OT) | 3-9 | .250 | - | | DeGol Arena · Loretto, PA |
| 14 | Wed Jan 27 | vsFairleigh | W90-82 | 4-9 | .308 | - | | DeGol Arena · Loretto, PA |
| 15 | Sat Jan 30 | vs C Connecticut | W62-59 | 5-9 | .357 | - | | DeGol Arena · Loretto, PA |
| 16 | Sun Jan 31 | vsC Connecticut | L77-85 | 5-10 | .333 | - | | DeGol Arena · Loretto, PA |
| 17 | Thu Feb 4 | at Merrimack | L62-68 | 5-11 | .313 | - | | placeholder · sf, ca |
| 18 | Fri Feb 5 | atMerrimack | L54-59 | 5-12 | .294 | - | | placeholder · sf, ca |
| 19 | Thu Feb 11 | vs St Francis BK | L67-70 | 5-13 | .278 | - | | DeGol Arena · Loretto, PA |
| 20 | Fri Feb 12 | vsSt Francis BK | W80-66 | 6-13 | .316 | - | | DeGol Arena · Loretto, PA |
| 21 | Sat Feb 20 | at Wagner | L52-67 | 6-14 | .300 | - | | Spiro Sports Center · Staten Island, NY |
| 22 | Sun Feb 21 | atWagner | L68-70 | 6-15 | .286 | - | | Spiro Sports Center · Staten Island, NY |
| 23 | Thu Feb 25 | vsMount St Mary | L65-72 (OT) | 6-16 | .273 | - | | DeGol Arena · Loretto, PA |
St Bonaventure