| 1 | Mon Nov 6 | at UCLA | L44-75 | - | 0-1 | .000 | - | | Pauley Pavilion · Los Angeles, CA |
| 2 | Thu Nov 9 | atSan Francisco | L52-84 | - | 0-2 | .000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 3 | Sat Nov 11 | atSanta Clara | L59-82 | - | 0-3 | .000 | - | | Leavey Center · Santa Clara, CA |
| 4 | Tue Nov 14 | atPenn State | L53-83 | - | 0-4 | .000 | - | Big Ten Network | Bryce Jordan Center · University Park, PA |
| 5 | Mon Nov 20 | vsTBD | W77-63 | - | 1-4 | .200 | - | | DeGol Arena · Loretto, PA |
| 6 | Wed Nov 22 | vsTBD | W107-54 | - | 2-4 | .333 | - | | DeGol Arena · Loretto, PA |
| 7 | Sat Nov 25 | vsNiagara | L61-69 | - | 2-5 | .286 | - | | DeGol Arena · Loretto, PA |
| 8 | Wed Nov 29 | atLehigh | W62-61 | - | 3-5 | .375 | - | | Stabler Arena · Bethlehem, PA |
| 9 | Sat Dec 2 | atAmerican | W75-73 | - | 4-5 | .444 | - | | Bender Arena · Washington, D.C. |
| 10 | Sun Dec 10 | atIona | L54-61 | - | 4-6 | .400 | - | | Hynes Athletics Center · New Rochelle, NY |
| 11 | Fri Dec 15 | vsMount St Mary | L65-72 | - | 4-7 | .364 | - | | DeGol Arena · Loretto, PA |
| 12 | Wed Dec 20 | vsRobert Morris | L73-75 | - | 4-8 | .333 | - | | DeGol Arena · Loretto, PA |
| 13 | Sat Dec 30 | vsCampbell | W78-76 | - | 5-8 | .385 | - | | DeGol Arena · Loretto, PA |
| 14 | Thu Jan 4 | atSacred Heart | L67-79 | - | 5-9 | .357 | - | | William H. Pitt Center · Fairfield, CT |
| 15 | Sat Jan 6 | atWagner | L56-71 | - | 5-10 | .333 | - | | Spiro Sports Center · Staten Island, NY |
| 16 | Sat Jan 13 | vsC Connecticut | L61-75 | - | 5-11 | .313 | - | | DeGol Arena · Loretto, PA |
| 17 | Mon Jan 15 | vsFairleigh | L71-81 | - | 5-12 | .294 | - | | DeGol Arena · Loretto, PA |
| 18 | Fri Jan 19 | vsLong Island | W72-66 | - | 6-12 | .333 | - | | DeGol Arena · Loretto, PA |
| 19 | Sun Jan 21 | atLe Moyne | L57-94 | - | 6-13 | .316 | - | | Ted Grant Court · Syracuse, NY |
| 20 | Thu Jan 25 | vsSacred Heart | W75-71 | - | 7-13 | .350 | - | | DeGol Arena · Loretto, PA |
| 21 | Sat Jan 27 | vsMerrimack | L55-74 | - | 7-14 | .333 | - | | DeGol Arena · Loretto, PA |
| 22 | Thu Feb 1 | atC Connecticut | L62-63 | - | 7-15 | .318 | - | | William H. Detrick Gymnasium · New Britain, CT |
| 23 | Sat Feb 3 | atLong Island | L67-70 | - | 7-16 | .304 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 24 | Sat Feb 10 | vsStonehill | W72-63 | - | 8-16 | .333 | - | | DeGol Arena · Loretto, PA |
| 25 | Thu Feb 15 | vsWagner | L63-65 (OT) | - | 8-17 | .320 | - | | DeGol Arena · Loretto, PA |
| 26 | Sat Feb 17 | atFairleigh | L74-93 | - | 8-18 | .308 | - | | Bogota Savings Bank Center · Teaneck, NJ |
| 27 | Thu Feb 22 | atMerrimack | L60-71 | - | 8-19 | .296 | - | | placeholder · sf, ca |
| 28 | Sat Feb 24 | atStonehill | L63-72 | - | 8-20 | .286 | - | | placeholder · sf, ca |
| 29 | Sat Mar 2 | vsLe Moyne | L58-74 | - | 8-21 | .276 | - | | DeGol Arena · Loretto, PA |
| 30 | Wed Mar 6 | atC Connecticut | L62-71 | - | 8-22 | .267 | - | | William H. Detrick Gymnasium · New Britain, CT |
