| 1 | Mon Nov 7 | at Mississippi St | L44-63 | 0-1 | .000 | - | | Humphrey Coliseum · Starkville, MS |
| 2 | Fri Nov 11 | vsUTSA | W75-55 | 1-1 | .500 | - | | American Bank Center · Corpus Christi, TX |
| 3 | Mon Nov 14 | vsTBD | W91-73 | 2-1 | .667 | - | | American Bank Center · Corpus Christi, TX |
| 4 | Thu Nov 17 | vsUT Rio Grande | W97-75 | 3-1 | .750 | - | | American Bank Center · Corpus Christi, TX |
| 5 | Tue Nov 22 | vsBakersfield | L63-73 | 3-2 | .600 | - | | Don Haskins Center · El Paso, TX |
| 6 | Wed Nov 23 | atAlcorn St | W98-67 | 4-2 | .667 | - | | Don Haskins Center · El Paso, TX |
| 7 | Fri Nov 25 | atUTEP | L67-72 | 4-3 | .571 | - | | Don Haskins Center · El Paso, TX |
| 8 | Wed Nov 30 | atUT Rio Grande | L82-89 | 4-4 | .500 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 9 | Wed Dec 7 | vsTBD | W100-63 | 5-4 | .556 | - | | American Bank Center · Corpus Christi, TX |
| 10 | Tue Dec 13 | at9Arizona | L61-99 | 5-5 | .500 | - | | McKale Center · Tucson, AZ |
| 11 | Fri Dec 16 | vsTBD | W104-69 | 6-5 | .545 | - | | American Bank Center · Corpus Christi, TX |
| 12 | Tue Dec 20 | atOklahoma St | L58-81 | 6-6 | .500 | - | | Gallagher-Iba Arena · Stillwater, OK |
| 13 | Wed Dec 28 | vsTBD | W88-74 | 7-6 | .538 | - | | American Bank Center · Corpus Christi, TX |
| 14 | Sat Dec 31 | atN'Western St | W65-59 | 8-6 | .571 | - | | Prather Coliseum · Natchitoches, LA |
| 15 | Wed Jan 4 | vsIncarnate Word | W91-61 | 9-6 | .600 | - | | American Bank Center · Corpus Christi, TX |
| 16 | Sat Jan 7 | atIncarnate Word | W80-71 | 10-6 | .625 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 17 | Thu Jan 12 | vsSE Louisiana | L82-85 (OT) | 10-7 | .588 | - | | American Bank Center · Corpus Christi, TX |
| 18 | Sat Jan 14 | vsNew Orleans | W97-79 | 11-7 | .611 | - | | American Bank Center · Corpus Christi, TX |
| 19 | Thu Jan 19 | atLamar | L66-68 | 11-8 | .579 | - | | Montagne Center · Beaumont, TX |
| 20 | Sat Jan 21 | atHou Christian | L78-90 | 11-9 | .550 | - | | Sharp Gymnasium · Houston, TX |
| 21 | Thu Jan 26 | vsNicholls | W96-86 | 12-9 | .571 | - | | American Bank Center · Corpus Christi, TX |
| 22 | Sat Jan 28 | vsMcNeese | W83-72 | 13-9 | .591 | - | | American Bank Center · Corpus Christi, TX |
| 23 | Thu Feb 2 | atNew Orleans | W86-69 | 14-9 | .609 | - | | Lakefront Arena · New Orleans, LA |
| 24 | Sat Feb 4 | atSE Louisiana | W83-72 | 15-9 | .625 | - | ESPNEWS | University Center (LA) · Hammond, LA |
| 25 | Thu Feb 9 | vsHou Christian | W91-68 | 16-9 | .640 | - | | American Bank Center · Corpus Christi, TX |
| 26 | Sat Feb 11 | vsLamar | W61-52 | 17-9 | .654 | - | | American Bank Center · Corpus Christi, TX |
| 27 | Thu Feb 16 | atNicholls | W78-74 | 18-9 | .667 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 28 | Sat Feb 18 | atMcNeese | W77-54 | 19-9 | .679 | - | | Legacy Center · Lake Charles, LA |
| 29 | Thu Feb 23 | vsE Texas A&M | L80-84 | 19-10 | .655 | - | | American Bank Center · Corpus Christi, TX |
| 30 | Sat Feb 25 | vsN'Western St | W83-75 | 20-10 | .667 | - | | American Bank Center · Corpus Christi, TX |
| 31 | Wed Mar 1 | atE Texas A&M | W93-88 (OT) | 21-10 | .677 | - | | The Field House · Commerce, TX |
| 32 | Tue Mar 7 | vsMcNeese | W80-63 | 22-10 | .688 | - | ESPNU | American Bank Center · Corpus Christi, TX |
| 33 | Wed Mar 8 | vsN'Western St | W75-71 | 23-10 | .697 | - | ESPN2 | American Bank Center · Corpus Christi, TX |
| 34 | Tue Mar 14 | vs16SE Missouri St | W75-71 | 24-10 | .706 | #16 | truTV | UD Arena · Dayton, OH |
| 35 | Thu Mar 16 | at1Alabama | L75-96 | 24-11 | .686 | #16 | CBS | Coleman Coliseum · Tuscaloosa, AL |
