| 1 | Tue Nov 9 | at Indiana | L62-68 | 0-1 | .000 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 2 | Fri Nov 12 | vsIllinois St | W103-98 (2OT) | 1-1 | .500 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 3 | Thu Nov 18 | atN Kentucky | L73-74 | 1-2 | .333 | - | | Truist Arena · Highland Heights, KY |
| 4 | Sat Nov 20 | atMichigan St | L59-83 | 1-3 | .250 | - | | Breslin Center · East Lansing, MI |
| 5 | Wed Nov 24 | vsW Illinois | W72-68 | 2-3 | .400 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 6 | Sun Nov 28 | atDePaul | L63-101 | 2-4 | .333 | - | FS1 | Wintrust Arena · Chicago, IL |
| 7 | Thu Dec 2 | atUC San Diego | L74-83 | 2-5 | .286 | - | | University Credit Union Center · Davis, CA |
| 8 | Sun Dec 5 | vsTBD | W79-57 | 3-5 | .375 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 9 | Wed Dec 8 | vsNiagara | W60-58 | 4-5 | .444 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 10 | Sat Dec 11 | vsFIU | W92-88 (4OT) | 5-5 | .500 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 11 | Mon Dec 20 | atValparaiso | L55-67 | 5-6 | .455 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 12 | Tue Dec 28 | atOhio | PPD | 10-21 | .323 | - | | Convocation Center (OH) · Athens, OH |
| 13 | Sat Jan 1 | vsBuffalo | PPD | 10-21 | .323 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 14 | Tue Jan 4 | atW Michigan | W85-79 | 6-6 | .500 | - | | University Arena (MI) · Kalamazoo, MI |
| 15 | Sat Jan 8 | vsBall State | L72-78 | 6-7 | .462 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 16 | Tue Jan 11 | vsC Michigan | W99-68 | 7-7 | .500 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 17 | Sat Jan 15 | atN Illinois | L70-77 | 7-8 | .467 | - | | NIU Convocation Center · Dekalb, IL |
| 18 | Tue Jan 18 | vsKent State | L47-56 | 7-9 | .438 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 19 | Sat Jan 22 | atAkron | L44-46 | 7-10 | .412 | - | | James A. Rhodes Arena · Akron, OH |
| 20 | Tue Jan 25 | atBowling Green | L71-85 | 7-11 | .389 | - | | Stroh Center · Bowling Green, OH |
| 21 | Sat Jan 29 | vsMiami OH | W85-75 | 8-11 | .421 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 22 | Tue Feb 1 | vsToledo | L66-86 | 8-12 | .400 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 23 | Thu Feb 3 | atOhio | L68-81 | 8-13 | .381 | - | | Convocation Center (OH) · Athens, OH |
| 24 | Sat Feb 5 | atKent State | L71-90 | 8-14 | .364 | - | | M.A.C. Center · Kent, OH |
| 25 | Tue Feb 8 | atBuffalo | L64-102 | 8-15 | .348 | - | | Alumni Arena · Buffalo, NY |
| 26 | Sat Feb 12 | vsOhio | L56-74 | 8-16 | .333 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 27 | Tue Feb 15 | atC Michigan | W75-70 | 9-16 | .360 | - | | McGuirk Arena · Mount Pleasant, MI |
| 28 | Thu Feb 17 | vsBuffalo | L69-83 | 9-17 | .346 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 29 | Sat Feb 19 | vsAkron | L48-67 | 9-18 | .333 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 30 | Tue Feb 22 | vsN Illinois | W74-72 | 10-18 | .357 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 31 | Sat Feb 26 | atBall State | L64-75 | 10-19 | .345 | - | | Worthen Arena · Muncie, IN |
| 32 | Tue Mar 1 | vsW Michigan | L60-71 | 10-20 | .333 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 33 | Fri Mar 4 | atMiami OH | L63-76 | 10-21 | .323 | - | | Millett Hall · Oxford, OH |
