| 1 | Wed Nov 25 | at West Virginia | L71-79 | 0-1 | .000 | - | ESPN2 | WVU Coliseum · Morgantown, WV |
| 2 | Thu Nov 26 | vs Utah State | W83-59 | 1-1 | .500 | - | ESPN2 | Frost Arena · Brookings, SD |
| 3 | Fri Nov 27 | at Saint Mary's | L59-72 | 1-2 | .333 | - | ESPN2 | University Credit Union Pavilion · Moraga, CA |
| 4 | Wed Dec 2 | at Iowa State | W71-68 | 2-2 | .500 | - | | James H. Hilton Coliseum · Ames, IA |
| 5 | Fri Dec 4 | at Bradley | W88-84 | 3-2 | .600 | - | | Carver Arena · Peoria, IL |
| 6 | Thu Dec 10 | vs N Dakota St | W77-75 | 4-2 | .667 | - | | Frost Arena · Brookings, SD |
| 7 | Fri Dec 11 | at North Dakota | W74-62 | 5-2 | .714 | - | | Betty Engelstad Sioux Center · Grand Forks, ND |
| 8 | Sat Dec 12 | vs South Dakota | L78-91 | 5-3 | .625 | - | | Frost Arena · Brookings, SD |
| 9 | Mon Jan 4 | vs TBD | W93-50 | 6-3 | .667 | - | | Frost Arena · Brookings, SD |
| 10 | Fri Jan 8 | vs W Illinois | W83-77 | 7-3 | .700 | - | | Frost Arena · Brookings, SD |
| 11 | Sat Jan 9 | vsW Illinois | W92-63 | 8-3 | .727 | - | | Frost Arena · Brookings, SD |
| 14 | Fri Jan 22 | vsNorth Dakota | W92-73 | 9-3 | .750 | - | | Frost Arena · Brookings, SD |
| 15 | Sat Jan 23 | vsNorth Dakota | W85-74 | 10-3 | .769 | - | | Frost Arena · Brookings, SD |
| 18 | Fri Feb 5 | vsSouth Dakota | L56-64 | 10-4 | .714 | - | | Frost Arena · Brookings, SD |
| 19 | Sat Feb 6 | vsSouth Dakota | W89-78 | 11-4 | .733 | - | | Frost Arena · Brookings, SD |
| 20 | Sat Feb 13 | at Oral Roberts | L86-103 | 11-5 | .688 | - | | Mabee Center · Tulsa, OK |
| 21 | Sun Feb 14 | atOral Roberts | W95-80 | 12-5 | .706 | - | | Mabee Center · Tulsa, OK |
| 22 | Fri Feb 19 | atN Dakota St | W68-67 | 13-5 | .722 | - | | Scheels Center · Fargo, ND |
| 23 | Sat Feb 20 | atN Dakota St | L82-84 | 13-6 | .684 | - | | Scheels Center · Fargo, ND |
| 24 | Fri Feb 26 | vs Kansas City | W67-49 | 14-6 | .700 | - | | Frost Arena · Brookings, SD |
| 25 | Sat Feb 27 | vsKansas City | W89-77 | 15-6 | .714 | - | | Frost Arena · Brookings, SD |
| 26 | Sat Mar 6 | vs Omaha | W84-71 | 16-6 | .727 | - | | Frost Arena · Brookings, SD |
| 27 | Mon Mar 8 | vsOral Roberts | L88-90 | 16-7 | .696 | - | | Frost Arena · Brookings, SD |
Denver