| 1 | Mon Nov 3 | at Merrimack | W75-66 | 1-0 | 1.000 | - | YouTube | placeholder · sf, ca |
| 2 | Thu Nov 6 | vsTBD | W68-62 | 2-0 | 1.000 | - | | Frost Arena · Brookings, SD |
| 3 | Sun Nov 9 | atNorthern Iowa | L58-65 | 2-1 | .667 | - | ESPN+ | McLeod Center · Cedar Falls, IA |
| 4 | Wed Nov 12 | atOregon | L69-83 | 2-2 | .500 | - | Peacock | Matthew Knight Arena · Eugene, OR |
| 5 | Mon Nov 17 | vsTBD | W94-46 | 3-2 | .600 | - | | Frost Arena · Brookings, SD |
| 6 | Fri Nov 21 | vsGeorgia St | W105-58 | 4-2 | .667 | - | | Frost Arena · Brookings, SD |
| 7 | Tue Nov 25 | vsUtah Valley | L52-75 | 4-3 | .571 | - | | Frost Arena · Brookings, SD |
| 8 | Wed Nov 26 | atUC Irvine | L52-64 | 4-4 | .500 | - | | Bren Events Center · Irvine, CA |
| 9 | Wed Dec 3 | atN Arizona | W75-62 | 5-4 | .556 | - | ESPN+ | J. Lawrence Walkup Skydome · Flagstaff, AZ |
| 10 | Sat Dec 6 | vsIdaho | L81-84 | 5-5 | .500 | - | | Frost Arena · Brookings, SD |
| 11 | Tue Dec 9 | atBall State | W68-64 | 6-5 | .545 | - | ESPN+ | Worthen Arena · Muncie, IN |
| 12 | Fri Dec 12 | vsTBD | W94-62 | 7-5 | .583 | - | | Frost Arena · Brookings, SD |
| 13 | Mon Dec 15 | vsWyoming | L72-87 | 7-6 | .538 | - | | Frost Arena · Brookings, SD |
| 14 | Fri Dec 19 | atMilwaukee | L87-88 | 7-7 | .500 | - | | Fiserv Forum · Milwaukee, WI |
| 15 | Mon Dec 29 | at1Arizona | L71-99 | 7-8 | .467 | - | ESPN+ | McKale Center · Tucson, AZ |
| 16 | Thu Jan 1 | vsOmaha | W84-69 | 8-8 | .500 | - | | Frost Arena · Brookings, SD |
| 17 | Sat Jan 3 | atNorth Dakota | L87-90 (OT) | 8-9 | .471 | - | | Betty Engelstad Sioux Center · Grand Forks, ND |
| 18 | Thu Jan 8 | vsDenver | W87-79 | 9-9 | .500 | - | | Frost Arena · Brookings, SD |
| 19 | Wed Jan 14 | atN Dakota St | L65-76 | 9-10 | .474 | - | | Scheels Center · Fargo, ND |
| 20 | Sat Jan 17 | vsKansas City | W90-62 | 10-10 | .500 | - | | Frost Arena · Brookings, SD |
| 21 | Thu Jan 22 | atSt Thomas (MN) | L69-74 | 10-11 | .476 | - | | Schoenecker Arena · Saint Paul, MN |
| 22 | Wed Jan 28 | atOmaha | L71-80 | 10-12 | .455 | - | | Baxter Arena · Omaha, NE |
| 23 | Sat Jan 31 | vsOral Roberts | W95-72 | 11-12 | .478 | - | | Frost Arena · Brookings, SD |
| 24 | Wed Feb 4 | vsSt Thomas (MN) | L62-77 | 11-13 | .458 | - | CBSSN | Frost Arena · Brookings, SD |
| 25 | Sat Feb 7 | vsSouth Dakota | L67-68 | 11-14 | .440 | - | CBSSN | Frost Arena · Brookings, SD |
| 26 | Thu Feb 12 | atDenver | L61-79 | 11-15 | .423 | - | | Hamilton Gymnasium · Denver, CO |
| 27 | Sat Feb 14 | atOral Roberts | W87-69 | 12-15 | .444 | - | | Mabee Center · Tulsa, OK |
| 28 | Wed Feb 18 | vsN Dakota St | L66-74 | 12-16 | .429 | - | | Frost Arena · Brookings, SD |
| 29 | Sat Feb 21 | vsNorth Dakota | W91-83 | 13-16 | .448 | - | | Frost Arena · Brookings, SD |
| 30 | Thu Feb 26 | atKansas City | W73-59 | 14-16 | .467 | - | | Swinney Recreation Center · Kansas City, MO |
| 31 | Sat Feb 28 | atSouth Dakota | L70-75 | 14-17 | .452 | - | | Sanford Coyote Sports Center · Vermillion, SD |
