| 1 | Mon Nov 6 | vs TBD | W110-59 | 1-0 | 1.000 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 2 | Fri Nov 10 | at South Dakota | L79-100 | 1-1 | .500 | - | | Sanford Coyote Sports Center · Vermillion, SD |
| 3 | Tue Nov 14 | at TCU | L55-88 | 1-2 | .333 | - | | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 4 | Fri Nov 17 | at Oklahoma | L66-90 | 1-3 | .250 | - | | Lloyd Noble Center · Norman, OK |
| 5 | Mon Nov 20 | vsTBD | W92-73 | 2-3 | .400 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 6 | Fri Nov 24 | at Hawai'i | L57-76 | 2-4 | .333 | - | | Stan Sheriff Center · Honolulu, HI |
| 7 | Sat Nov 25 | vs Arkansas St | L58-75 | 2-5 | .286 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 8 | Wed Nov 29 | vs Grand Canyon | L69-79 | 2-6 | .250 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 9 | Sat Dec 2 | at Tarleton | L75-77 | 2-7 | .222 | - | | placeholder · sf, ca |
| 10 | Wed Dec 6 | at Texas A&M-CC | W76-74 | 3-7 | .300 | - | | American Bank Center · Corpus Christi, TX |
| 11 | Fri Dec 15 | vsTexas A&M-CC | L76-86 | 3-8 | .273 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 12 | Mon Dec 18 | at Chicago St | L68-78 | 3-9 | .250 | - | | Jones Convocation Center · Chicago, IL |
| 13 | Sat Dec 30 | vs Incarnate Word | W77-74 | 4-9 | .308 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 14 | Thu Jan 4 | vs SF Austin | L78-85 | 4-10 | .286 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 15 | Sat Jan 6 | at Abilene Chrstn | L89-91 (OT) | 4-11 | .267 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 16 | Thu Jan 11 | vs Seattle U | W81-80 (OT) | 5-11 | .313 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 17 | Sat Jan 13 | vs Utah Valley | W76-68 | 6-11 | .353 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 18 | Thu Jan 18 | at UT Arlington | L73-91 | 6-12 | .333 | - | | College Park Center · Arlington, TX |
| 19 | Sat Jan 20 | vsTarleton | L73-77 | 6-13 | .316 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 20 | Thu Jan 25 | vs CA Baptist | L54-63 | 6-14 | .300 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 21 | Thu Feb 1 | at Utah Tech | L64-81 | 6-15 | .286 | - | | placeholder · sf, ca |
| 22 | Sat Feb 3 | at Southern Utah | L59-79 | 6-16 | .273 | - | | America First Events Center · Cedar City, UT |
| 23 | Thu Feb 8 | atSF Austin | L84-92 | 6-17 | .261 | - | | William R. Johnson Coliseum · Nacogdoches, TX |
| 24 | Thu Feb 15 | vsAbilene Chrstn | L79-87 | 6-18 | .250 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 25 | Sat Feb 17 | vsUT Arlington | L70-89 | 6-19 | .240 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 26 | Thu Feb 22 | atUtah Valley | L59-70 | 6-20 | .231 | - | | UCCU Center · Orem, UT |
| 27 | Sat Feb 24 | atSeattle U | L56-84 | 6-21 | .222 | - | | Redhawk Center · Seattle, WA |
| 28 | Thu Feb 29 | atGrand Canyon | L43-72 | 6-22 | .214 | - | | GCU Arena · Phoenix, AZ |
| 29 | Sat Mar 2 | atCA Baptist | L52-88 | 6-23 | .207 | - | | CBU Events Center · Riverside, CA |
| 30 | Thu Mar 7 | vsUtah Tech | L74-79 | 6-24 | .200 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 31 | Sat Mar 9 | vsSouthern Utah | L59-68 | 6-25 | .194 | - | | UTRGV Fieldhouse · Edinburg, TX |
