| 1 | Mon Nov 7 | at Towson | L62-67 | 0-1 | .000 | - | | SECU Arena · Towson, MD |
| 2 | Tue Nov 8 | atTBD | W74-47 | 1-1 | .500 | - | | Alumnae Gymnasium |
| 3 | Sat Nov 12 | atSiena | L62-75 | 1-2 | .333 | - | | MVP Arena · Albany, NY |
| 4 | Mon Nov 14 | vsTBD | W87-75 | 2-2 | .500 | - | | SEFCU Arena · Albany, NY |
| 5 | Thu Nov 17 | atSaint Joseph's | L79-99 | 2-3 | .400 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 6 | Mon Nov 21 | vsAustin Peay | L59-74 | 2-4 | .333 | - | | SEFCU Arena · Albany, NY |
| 7 | Tue Nov 22 | atPresbyterian | W68-65 | 3-4 | .429 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 8 | Sat Nov 26 | vsFAU | L56-73 | 3-5 | .375 | - | | SEFCU Arena · Albany, NY |
| 9 | Tue Nov 29 | atAmerican | L62-88 | 3-6 | .333 | - | | Bender Arena · Washington, D.C. |
| 10 | Mon Dec 5 | atUMass | L73-87 | 3-7 | .300 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 11 | Sat Dec 10 | atProvidence | L55-93 | 3-8 | .273 | - | FS1 | Amica Mutual Pavilion · Providence, RI |
| 12 | Wed Dec 14 | vsLong Island | W76-59 | 4-8 | .333 | - | | SEFCU Arena · Albany, NY |
| 13 | Sun Dec 18 | atLoyola Chicago | L56-68 | 4-9 | .308 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 14 | Tue Dec 20 | atN Illinois | W83-78 | 5-9 | .357 | - | | NIU Convocation Center · Dekalb, IL |
| 15 | Wed Dec 28 | at13Virginia | L46-66 | 5-10 | .333 | - | ACC Network | John Paul Jones Arena · Charlottesville, VA |
| 16 | Sat Dec 31 | vsNew Hampshire | L51-67 | 5-11 | .313 | - | | SEFCU Arena · Albany, NY |
| 17 | Thu Jan 5 | atUMBC | L83-92 | 5-12 | .294 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 18 | Sun Jan 8 | vsUMass Lowell | W89-63 | 6-12 | .333 | - | | SEFCU Arena · Albany, NY |
| 19 | Wed Jan 11 | atBryant | L69-86 | 6-13 | .316 | - | | Chace Athletic Center · Smithfield, RI |
| 20 | Sat Jan 14 | atNJIT | L67-74 | 6-14 | .300 | - | | NJIT Wellness and Events Center · Newark, NJ |
| 21 | Thu Jan 19 | vsBinghamton | L54-65 | 6-15 | .286 | - | | SEFCU Arena · Albany, NY |
| 22 | Wed Jan 25 | atNew Hampshire | L65-84 | 6-16 | .273 | - | | Lundholm Gymnasium · Durham, NH |
| 23 | Sat Jan 28 | vsMaine | L68-72 | 6-17 | .261 | - | | SEFCU Arena · Albany, NY |
| 24 | Wed Feb 1 | atUMass Lowell | L50-66 | 6-18 | .250 | - | | Costello Athletic Center · Lowell, MA |
| 25 | Sat Feb 4 | vsVermont | L68-87 | 6-19 | .240 | - | | SEFCU Arena · Albany, NY |
| 26 | Wed Feb 8 | vsBryant | L62-87 | 6-20 | .231 | - | | SEFCU Arena · Albany, NY |
| 27 | Sat Feb 11 | atBinghamton | L66-80 (OT) | 6-21 | .222 | - | | Events Center (Binghamton) · Binghamton, NY |
| 28 | Wed Feb 15 | vsUMBC | W81-74 | 7-21 | .250 | - | | SEFCU Arena · Albany, NY |
| 29 | Sat Feb 18 | atMaine | L72-74 | 7-22 | .241 | - | | Cross Insurance Center · Bangor, ME |
| 30 | Sat Feb 25 | vsNJIT | W82-68 | 8-22 | .267 | - | | SEFCU Arena · Albany, NY |
| 31 | Tue Feb 28 | atVermont | L61-79 | 8-23 | .258 | - | | Patrick Gymnasium · Burlington, VT |
