| 1 | Wed Nov 25 | at N Kentucky | L73-74 | 0-1 | .000 | - | | Truist Arena · Highland Heights, KY |
| 2 | Wed Dec 2 | atMichigan | L65-84 | 0-2 | .000 | - | BTN | Crisler Center · Ann Arbor, MI |
| 3 | Sat Dec 5 | vsUIC | W68-66 | 1-2 | .333 | - | | Worthen Arena · Muncie, IN |
| 4 | Tue Dec 8 | atN Illinois | W79-70 (OT) | 2-2 | .500 | - | | NIU Convocation Center · Dekalb, IL |
| 5 | Sat Dec 12 | vsIllinois St | W82-66 | 3-2 | .600 | - | | Worthen Arena · Muncie, IN |
| 6 | Sat Dec 19 | atIndiana St | L57-67 | 3-3 | .500 | - | | Hulman Center · Terre Haute, IN |
| 7 | Tue Dec 22 | atW Michigan | W76-68 | 4-3 | .571 | - | | University Arena (MI) · Kalamazoo, MI |
| 8 | Sat Jan 2 | vsOhio | L68-78 | 4-4 | .500 | - | CBSSN | Worthen Arena · Muncie, IN |
| 10 | Sat Jan 9 | atBuffalo | L69-86 | 4-5 | .444 | - | | Alumni Arena · Buffalo, NY |
| 11 | Tue Jan 12 | atBowling Green | W88-64 | 5-5 | .500 | - | | Stroh Center · Bowling Green, OH |
| 12 | Sat Jan 16 | vsN Illinois | W78-58 | 6-5 | .545 | - | | Worthen Arena · Muncie, IN |
| 13 | Tue Jan 19 | atMiami OH | L71-81 | 6-6 | .500 | - | | Millett Hall · Oxford, OH |
| 14 | Fri Jan 22 | atOhio | PPD | 10-13 | .435 | - | CBSSN | Convocation Center (OH) · Athens, OH |
| 15 | Sat Jan 23 | atOhio | L77-85 | 6-7 | .462 | - | | Convocation Center (OH) · Athens, OH |
| 16 | Tue Jan 26 | vsKent State | PPD | 10-13 | .435 | - | | Worthen Arena · Muncie, IN |
| 17 | Sat Jan 30 | atAkron | L42-74 | 6-8 | .429 | - | | James A. Rhodes Arena · Akron, OH |
| 18 | Tue Feb 2 | vsBuffalo | L58-78 | 6-9 | .400 | - | | Worthen Arena · Muncie, IN |
| 19 | Sat Feb 6 | vsToledo | W81-67 | 7-9 | .438 | - | CBSSN | Worthen Arena · Muncie, IN |
| 20 | Tue Feb 9 | atC Michigan | PPD | 10-13 | .435 | - | | McGuirk Arena · Mount Pleasant, MI |
| 21 | Sat Feb 13 | vsE Michigan | PPD | 10-13 | .435 | - | | Worthen Arena · Muncie, IN |
| 22 | Tue Feb 16 | vsBowling Green | L62-75 | 7-10 | .412 | - | | Worthen Arena · Muncie, IN |
| 23 | Fri Feb 19 | vsAkron | L79-88 | 7-11 | .389 | - | CBSSN | Worthen Arena · Muncie, IN |
| 25 | Wed Feb 24 | vsKent State | W90-71 | 8-11 | .421 | - | | Worthen Arena · Muncie, IN |
| 26 | Sat Feb 27 | vsC Michigan | W97-91 | 9-11 | .450 | - | | Worthen Arena · Muncie, IN |
| 27 | Tue Mar 2 | vsE Michigan | W100-65 | 10-11 | .476 | - | | Worthen Arena · Muncie, IN |
| 28 | Fri Mar 5 | atToledo | L70-89 | 10-12 | .455 | - | | Savage Arena · Toledo, OH |
| 29 | Thu Mar 11 | atToledo | L89-91 (OT) | 10-13 | .435 | - | | Savage Arena · Toledo, OH |
