| 1 | Mon Nov 7 | at Oregon | L45-80 | 0-1 | .000 | - | | Matthew Knight Arena · Eugene, OR |
| 2 | Wed Nov 9 | atPortland | L54-91 | 0-2 | .000 | - | | Chiles Center · Portland, OR |
| 3 | Fri Nov 11 | atOregon St | L43-60 | 0-3 | .000 | - | | Gill Coliseum · Corvallis, OR |
| 4 | Tue Nov 15 | atMiami | L61-87 | 0-4 | .000 | - | | Watsco Center · Coral Gables, FL |
| 5 | Mon Nov 21 | vsTBD | W70-65 (OT) | 1-4 | .200 | - | | Al Lawson Center · Tallahassee, FL |
| 6 | Wed Nov 30 | atFlorida | L62-102 | 1-5 | .167 | - | | O'Connell Center · Gainesville, FL |
| 7 | Fri Dec 2 | atGeorgia | L46-68 | 1-6 | .143 | - | | Stegeman Coliseum · Athens, GA |
| 8 | Tue Dec 13 | vsTBD | W58-47 | 2-6 | .250 | - | | Al Lawson Center · Tallahassee, FL |
| 9 | Sat Dec 17 | atLouisville | L55-61 | 2-7 | .222 | - | | KFC Yum! Center · Louisville, KY |
| 10 | Wed Dec 21 | at19Kentucky | L68-88 | 2-8 | .200 | - | SEC Network | Rupp Arena · Lexington, KY |
| 11 | Thu Dec 29 | at1Purdue | L49-82 | 2-9 | .182 | - | BTN | Mackey Arena · West Lafayette, IN |
| 12 | Mon Jan 2 | vsBethune | L59-67 | 2-10 | .167 | - | | Al Lawson Center · Tallahassee, FL |
| 13 | Sat Jan 7 | atSouthern | L66-84 | 2-11 | .154 | - | | F. G. Clark Activity Center · Baton Rouge, LA |
| 14 | Mon Jan 9 | atGrambling | L57-62 | 2-12 | .143 | - | | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 15 | Sat Jan 14 | vsAR-Pine Bluff | L54-67 | 2-13 | .133 | - | | Al Lawson Center · Tallahassee, FL |
| 16 | Mon Jan 16 | vsMiss Valley St | W60-59 | 3-13 | .188 | - | | Al Lawson Center · Tallahassee, FL |
| 17 | Sat Jan 21 | atAlcorn St | L47-57 | 3-14 | .176 | - | | Davey L. Whitney Complex · Lorman, MS |
| 18 | Mon Jan 23 | atJackson St | L58-59 | 3-15 | .167 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 19 | Sat Jan 28 | vsAlabama A&M | L56-61 | 3-16 | .158 | - | | Al Lawson Center · Tallahassee, FL |
| 20 | Mon Jan 30 | vsAlabama St | W69-58 | 4-16 | .200 | - | | Al Lawson Center · Tallahassee, FL |
| 21 | Sat Feb 4 | atTexas So | W76-69 | 5-16 | .238 | - | | H&PE Arena · Houston, TX |
| 22 | Mon Feb 6 | atPrairie View | L45-75 | 5-17 | .227 | - | | William Nicks Building · Prairie View, TX |
| 23 | Sat Feb 11 | vsJackson St | L58-69 | 5-18 | .217 | - | | Al Lawson Center · Tallahassee, FL |
| 24 | Mon Feb 13 | vsAlcorn St | L64-67 | 5-19 | .208 | - | | Al Lawson Center · Tallahassee, FL |
| 25 | Sat Feb 18 | atAlabama St | W60-54 | 6-19 | .240 | - | | Dunn-Oliver Acadome · Montgomery, AL |
| 26 | Mon Feb 20 | atAlabama A&M | W77-71 | 7-19 | .269 | - | ESPNU | T.M. Elmore Gymnasium · Normal, AL |
| 27 | Sat Feb 25 | vsGrambling | L55-69 | 7-20 | .259 | - | | Al Lawson Center · Tallahassee, FL |
| 28 | Mon Feb 27 | vsSouthern | L58-60 | 7-21 | .250 | - | | Al Lawson Center · Tallahassee, FL |
| 29 | Sat Mar 4 | atBethune | L70-91 | 7-22 | .241 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
